KERRIE ZIEGLER
Pharmacy in Elm, NJ

License number
Pennsylvania PI107831
Category
Pharmacy
Type
Pharmacy Intern
Address
Address 2
Elm, NJ 08037
Pennsylvania

Professional information

Kerrie Ziegler Photo 1

Fast Dissolving Films For Oral Administration Of Drugs

US Patent:
2004020, Oct 21, 2004
Filed:
Dec 23, 2003
Appl. No.:
10/744479
Inventors:
David Friend - Princeton NJ, US
Aaron Levine - Lawrenceville NJ, US
Kerrie Ziegler - Hammonton NJ, US
Emmanuel Manna - Monmouth Junction NJ, US
International Classification:
A61K009/24
US Classification:
424/471000
Abstract:
A dosage unit comprises a substrate comprising a first polymer; a deposit, including an active ingredient; and a cover layer comprising a second polymer, wherein the cover layer covers the deposit and is joined to the first surface of the substrate by a bond that encircles the deposit and wherein at least one of the first and second polymers is a graft co-polymer. The dosage unit wherein said first and second polymers may be the same, and also the graft co-polymer may be a polyvinyl alcohol-polyethylene glycol graft co-polymer. Also disclosed is a dosage unit wherein the deposit is formed on the substrate by electrostatic dry drug deposition. The dosage unit may also include a polymer that is a graft co-polymer; and an active ingredient, and the graft co-polymer may be polyvinyl alcohol-polyethylene glycol.


Kerrie Ziegler Photo 2

Controlled-Release Drug Delivery System

US Patent:
2005001, Jan 27, 2005
Filed:
Jan 26, 2004
Appl. No.:
10/764786
Inventors:
Thomas Deveney - Browns Mills NJ, US
David Friend - Princeton NJ, US
George Pawlo - Long Valley NJ, US
Kerrie Ziegler - Hammonton NJ, US
International Classification:
A61K009/22
US Classification:
424468000, 604890100
Abstract:
A controlled-release drug delivery system advantageously includes an open-ended, inflexible sleeve, at least two controlled-release layers and two open-center caps. Each controlled-release layer abuts a sealing surface that is located within and near each end of the sleeve. The caps seal each controlled-release layer against the abutting sealing surface. One or more dose units of drug are disposed in a region that is formed between the controlled-release layers. The controlled-release layers dissolve, at a predetermined rate, by the action of body fluids that are in contact with those layers through the center of the caps. Release of drug is delayed at least until the controlled-release layers dissolve. The dose unit itself, which is advantageously a core, can be tailored to provide an extended period of drug release. One or more dose units that provide an immediate release component can also be disposed near each end of the sleeve.