Inventors:
George Vratsanos - Yardley PA, US
Francisco Leon - Bethesda MD, US
Lee Tay - Princeton Junction NJ, US
Kenneth Bahrt - Edison NJ, US
International Classification:
A61K 39/145, A61K 39/02, A61P 31/16
US Classification:
424209100, 424236100, 424244100
Abstract:
The present invention relates to methods of vaccinating subjects receiving immune modulating therapy, such as soluble CTLA4 molecules, for treatment of immune system diseases mediated by T-cell interactions with B7-positive cells including, but not limited to, autoimmune diseases, immunoproliferative diseases, and immune disorders associated with graft transplantation.