Inventors:
Brian R. MacDonald - Bryn Mawr PA, US
Kenneth Kaushansky - Del Mar CA, US
Assignee:
Janssen Pharmaceutica, N.V. - Beerse
International Classification:
A61K 38/02, C12N 5/00
US Classification:
514 78, 424 851, 4241981, 424 931, 424 937, 435325, 514 79, 530300
Abstract:
A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.