Inventors:
Kenneth K. Lew - Brookline MA
International Classification:
C12P 2100, C12N 1500, A01K 4500, A61K 3900
Abstract:
An easily cultured worm is genetically modified such that its surface antigens on its modified form are immunologically identical to the surface antigens of a parasitic worm. Specifically, C. elegans is genetically modified to produce antigens corresponding to the antigens of D. immitis which causes heartworm infection. The antigens derived from the easily cultured worm are used to form a vaccine and/or diagnostic.