KENNETH B PLATT
Veterinary in Ames, IA
License number
New Jersey 29VI00121800
Issued Date
Feb 2, 1968
Expiration Date
Jun 30, 1981
Category
Veterinary Medical Examiners
Type
Veterinarian
Address
Address
Ames, IA
Professional information
Lectin-Containing Anti-Viral Vaccines For Domestic Animals And Method Of Preparation
US Patent:
4470967, Sep 11, 1984
Filed:
Oct 5, 1982
Appl. No.:
6/432820
Inventors:
Patricia M. Gough - Ames IA
Kenneth B. Platt - Ames IA
Kenneth B. Platt - Ames IA
Assignee:
Iowa State University Research Foundation - Ames IA
International Classification:
A61K 3912
US Classification:
424 89
Abstract:
Anti-viral vaccines for domestic animals are prepared from glycoprotein envelope whole virus or antigenic glycoprotein obtained therefrom by complexing the glycoprotein antigenic agent with a lectin, which is preferably a mitogenic lectin. The recovery of the immunizing agent from an aqueous solution or suspension is facilitated since the lectin-glycoprotein complex is readily recoverable. The mitogenic lectin administered in the vaccine with the glycoprotein antigen can enhance the anamnestic response, in effect, acting as an adjuvant.
Immunoassay For Antibodies To Pseudorabies Virus Using Medium-Elaborated Viral Antigenic Factor
US Patent:
4820629, Apr 11, 1989
Filed:
Oct 22, 1985
Appl. No.:
6/790130
Inventors:
Kenneth B. Platt - Ames IA
Assignee:
Iowa State University Research Foundation, Inc. - Ames IA
International Classification:
C12Q 170, G01N 33535
US Classification:
435 5
Abstract:
Swine serum is tested for antibodies to pseudorabies (PR) virus by an immunoassay using a specific supernatant-elaborated PR virus antigen which is antigenically distinct from the lectin-binding glycoproteins of PR virus.
Purified And Antigenically Selective Vaccines For Domestic Animals
US Patent:
4493825, Jan 15, 1985
Filed:
Oct 5, 1982
Appl. No.:
6/432967
Inventors:
Kenneth B. Platt - Ames IA
David E. Reed - Ames IA
David E. Reed - Ames IA
Assignee:
Iowa State University Research Foundation - Ames IA
International Classification:
A61K 3900, A61K 3912, A61K 3902
US Classification:
424 88
Abstract:
Purified antigenically selective vaccines for domestic animals are prepared from microorganism cultures containing the immunizing agent by first complexing the immunizing agent with micro-particles having bound IgG antibodies specific for the immunizing agent, separating the resulting complex, and preparing a vaccine directly therefrom containing the antigen-antibody complex. The micro-particles preferably have Protein A in their outer surfaces for binding to the specific antibodies. The complex-containing vaccines provide effective immunization. The method and the resulting vaccines are particularly useful in preparing viral and bacterial subunit vaccines.
Method Of Detecting Pseudorabies Virus Specific Serum Antibody By Use Of A Universal Diagnostic Antigen
US Patent:
5122447, Jun 16, 1992
Filed:
Jan 23, 1989
Appl. No.:
7/299990
Inventors:
Michael J. McGinley - Ames IA
Kenneth B. Platt - Ames IA
Kenneth B. Platt - Ames IA
Assignee:
Iowa State University Research Foundation, Inc. - Ames IA
International Classification:
G01N 33569
US Classification:
435 5
Abstract:
A method of testing serum from swine vaccinated against pseudorabies virus with viral envelope-based subunit vaccines to determine the presence of antibodies to infecting pseudorabies virus in wihch an immunoassay is performed on the swine serum using a pseudorabies virus antigen preparation comprising nucleocapsid proteins of the pseudorabies virus. The universal diagnostic antigen is one or more nucleocapsid proteins having relative molecular weights of approximately 23 k, 34 k, 41 k, 63 k and 140 k.