KENNETH ARNO KRAMER
Pharmacy in Green Lane, PA
License number
Pennsylvania RP030982L
Category
Pharmacy
Type
Pharmacist
Address
Address
Green Lane, PA 18054
Professional information
Dry Mix Formulation For Bisphosphonic Acids
US Patent:
6406714, Jun 18, 2002
Filed:
Oct 17, 2000
Appl. No.:
09/690540
Inventors:
Simon R. Bechard - Quebec, CA
Kenneth A. Kramer - Green Lane PA
Ashok V. Katdare - Norristown PA
Kenneth A. Kramer - Green Lane PA
Ashok V. Katdare - Norristown PA
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
A61K 920
US Classification:
424464, 424465
Abstract:
Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Pagets disease, malignant hypercalcemia, and metastatic bone disease.
Wet Granulation Formulation For Bisphosphonic Acids
US Patent:
6692764, Feb 17, 2004
Filed:
Sep 23, 2002
Appl. No.:
10/252755
Inventors:
Ashok V. Katdare - Norristown PA
Kenneth A. Kramer - Green Lane PA
Kenneth A. Kramer - Green Lane PA
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
A61K 920
US Classification:
424465, 424469, 424470, 514108, 514114, 514210, 562 13, 562 14, 562 18
Abstract:
Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Pagets disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
Wet Granulation Formulation For Bisphosphonic Acids
US Patent:
2004013, Jul 15, 2004
Filed:
Dec 19, 2003
Appl. No.:
10/742229
Inventors:
Ashok Katdare - Norristown PA, US
Kenneth Kramer - Green Lane PA, US
Kenneth Kramer - Green Lane PA, US
International Classification:
A61K031/675, A61K009/20, A61K031/66
US Classification:
424/465000, 514/089000, 514/102000, 264/109000
Abstract:
Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
Dry Mix Formulation For Bisphosphonic Acids
US Patent:
6194004, Feb 27, 2001
Filed:
Nov 2, 1999
Appl. No.:
9/432859
Inventors:
Simon R. Bechard - Quebec, CA
Kenneth A. Kramer - Green Lane PA
Ashok V. Katdare - Norristown PA
Kenneth A. Kramer - Green Lane PA
Ashok V. Katdare - Norristown PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 920, A01N 5702
US Classification:
424464
Abstract:
Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
Effervescent Bisphosphonate Formulation
US Patent:
2004013, Jul 15, 2004
Filed:
Jan 5, 2004
Appl. No.:
10/751791
Inventors:
Ashok Katdare - Norristown PA, US
Kenneth Kramer - Green Lane PA, US
Colin Gardner - Blue Bell PA, US
Kenneth Kramer - Green Lane PA, US
Colin Gardner - Blue Bell PA, US
International Classification:
A61K031/675, A61K031/66, A61K009/46
US Classification:
424/466000, 514/102000, 514/089000
Abstract:
An effervescent formulation of alendronate contains an acid source, a carbonate source, a binder, a lubricant and optionally, flavoring agents, colorants and sweeteners.
Pharmaceutical Tablet
US Patent:
D380825, Jul 8, 1997
Filed:
Oct 31, 1994
Appl. No.:
D/030494
Inventors:
Kenneth A. Kramer - Green Lane PA
Ashok Katdare - Norristown PA
Ashok Katdare - Norristown PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
2801
US Classification:
D24101
Effer-Vescent Bisphosphonate Formulation
US Patent:
2003000, Jan 2, 2003
Filed:
Jul 9, 2002
Appl. No.:
10/191669
Inventors:
Ashok Katdare - Norristown PA, US
Colin Gardner - Blue Bell PA, US
Kenneth Kramer - Green Lane PA, US
Colin Gardner - Blue Bell PA, US
Kenneth Kramer - Green Lane PA, US
Assignee:
Merck & Co., Inc.
International Classification:
A61K031/66, A61L009/04, A61K009/46
US Classification:
424/466000, 424/044000, 514/102000
Abstract:
An effervescent formulation of alendronate contains an acid source, a carbonate source, a binder, a lubricant and optionally, flavoring agents, colorants and sweeteners.
Pharmaceutical Tablet
US Patent:
D406720, Nov 3, 1998
Filed:
Mar 21, 1996
Appl. No.:
D/052038
Inventors:
Kenneth A. Kramer - Green Lane PA
Ashok V. Katdare - Norristown PA
Ashok V. Katdare - Norristown PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
2801
US Classification:
D24101
Effervescent Bisphosphonate Formulation
US Patent:
2006003, Feb 16, 2006
Filed:
Oct 19, 2005
Appl. No.:
11/253392
Inventors:
Ashok Katdare - Norristown PA, US
Kenneth Kramer - Green Lane PA, US
Colin Gardner - Blue Bel PA, US
Kenneth Kramer - Green Lane PA, US
Colin Gardner - Blue Bel PA, US
International Classification:
A61K 31/663, A61K 9/46
US Classification:
424466000, 514102000
Abstract:
An effervescent formulation of alendronate contains an acid source, a carbonate source, a binder, a lubricant and optionally, flavoring agents, colorants and sweeteners.
Pharmaceutical Tablet
US Patent:
D379223, May 13, 1997
Filed:
Sep 13, 1995
Appl. No.:
D/043867
Inventors:
Kenneth A. Kramer - Green Lane PA
Ashok V. Katdare - Norristown PA
Ashok V. Katdare - Norristown PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
2801
US Classification:
D24101