Inventors:
Kenichi Fujise - Galveston TX, US
Nongporn Towatana - Hat Yai, TH
Wilawan Mahabusarakam - Songkhia, TH
International Classification:
A61K 39/395, A61K 31/352, A61K 31/40, A61K 31/4418, A61K 31/405, A61K 31/47, A61K 31/505, A61K 31/616, A61K 31/4365, A61K 31/519, A61P 9/10, A61P 3/06, A61P 7/02
US Classification:
4241331, 514456, 514423, 514277, 514415, 514311, 514275, 514161, 514301, 5142621
Abstract:
Provided herein are methods of treating postangiplasty, in-stent restenosis or atherosclerosis in an individual in need of such treatment, comprising the step of administering to said individual an effective dose of morelloflavone with or with a effective dose of one or more of an HMG-CoA reductase inhibitor or a hypolipidemic agent or lipid-lowering agent or other lipid agent or lipid modulating agent or anti-atherosclerotic agent. Also provided are pharmaceutical compositions comprising a morelloflavone or pharmaceutical combinations comprising a morelloflavone and one of an HMG-CoA reductase inhibitor or a hypolipidemic agent or lipid-lowering agent or other lipid agent or lipid modulating agent or anti-atherosclerotic agent.