Inventors:
Kendall A. Smith - New York NY
Carol Beadling - London, GB
Assignee:
Trustees of Dartmouth College - Hanover NH
International Classification:
C12N 1513, C12N 1563, C07K 14435, C07K 1542
Abstract:
Early-induced genes by interleukin-2 (IL-2) have various DNA sequences. This patent describes a nucleotide segment, such as SEQ. ID No: 11, SEQ. ID No. 31, or encoding a polypeptide of amino acids 1-159 of SEQ. ID No: 12, antibody binding homologues thereof, antibody binding fragments, and fusion proteins thereof, alleles or naturally occurring mutants of the polyribonucleotides, and anti-sense polyribonucleotides thereof. Also provided are proteins, homologues, fragments, fusion proteins, vectors, transfected hosts, animal models, probes, and other related technology.