Center For Medical Genetics 7400 Fannin St STE 700, Houston 77054 Houston Northwest Medical Center 710 Fm 1960 Rd West, Houston 77090 Memorial Hermann Healthcare System - Southwest 7600 Beechnut St, Houston 77074
Education:
Medical School Medical College Of Wisconsin Graduated: 1990
Methods And Systems To Determine Fetal Sex And Detect Fetal Abnormalities
US Patent:
2008010, May 8, 2008
Filed:
Oct 9, 2007
Appl. No.:
11/869064
Inventors:
Katherine Thompson - Houston TX, US
International Classification:
C12Q 1/68, A61B 8/13
US Classification:
435006000, 600443000
Abstract:
Non-invasive methods for determining the sex of a human fetus and predicting other genetic abnormalities are disclosed. The methods include screening a maternal sample for biomarkers known to be associated with risk of genetic abnormalities; removing all or substantially all nucleated and anucleated cell populations from the maternal sample to obtain a remaining material; detecting in the remaining material, the presence of nucleic acid; and determining the sex of the fetus from the nucleic acid wherein the presence of a certain marker is indicative of a male fetus; performing an ultrasound scan which yields quantitative measurements of the fetus; and interpreting the results of the genetic abnormality screening in conjunction with the ultrasound measurements.