Inventors:
Harold Meckler - Delmar NY, US
Karl Popp - Schodack Landing NY, US
Bingidimi Mobele - Altamont NY, US
Paul Isbester - Castleton NY, US
Bruce Elder - Wynantskill NY, US
Paul Vogt - Arlington Heights IL, US
Benjamin Littler - Mount Prospect IL, US
Stephen Eastham - Rexford NY, US
David Reed - Clifton Park NY, US
Luckner Ulysse - Albany NY, US
Michael Uttley - Delmar NY, US
International Classification:
A61K 31/16, C07C 233/24
Abstract:
Processes for preparing an amine compound by catalytically hydrogenating a precursor nitrile compound. In a particular aspect, the present hydrogenation process occurs in a dipolar organic solvent in the presence of a palladium/carbon catalyst and a strong anhydrous protic acid. In a further aspect, the preferred embodiment relates to a process for deprotecting a compound to produce an amine compound. In yet a further aspect, the preferred embodiment relates to amine products produced by the present processes. These amine products may be used for a variety of purposes.