KAREN J KLAMERUS
Pharmacy in San Diego, CA
License number
Pennsylvania RP036338R
Category
Pharmacy
Type
Pharmacist
Address
Address
2
San Diego, CA 92130
Pennsylvania
Pennsylvania
Professional information
Senior Director At Pfizer, Inc
Position:
Senior Director at Pfizer, Inc
Location:
Greater San Diego Area
Industry:
Pharmaceuticals
Work:
Pfizer, Inc
- Greater San Diego Area since 2004
-
Senior Director
Pfizer, Inc
- Greater San Diego Area 2002 - 2004
-
Director, Clinical Development
Vical, Inc
- Greater San Diego Area 2002 - 2002
-
Director, Clinical Research & Data Management
Hoffmann-La Roche
1997 - 2001
-
Director, Medical Research
Wyeth Research
- Radnor, Pennsylvania 1995 - 1997
-
Associate Director
Education:
University of Illinois at Chicago
BS, Pharmacy University of Kentucky
Pharm.D., Pharmacy University of Nebraska at Omaha
Residency, Pharmacy
BS, Pharmacy University of Kentucky
Pharm.D., Pharmacy University of Nebraska at Omaha
Residency, Pharmacy
Therapeutic Combinations Comprising Poly (Adp-Ribose) Polymerases Inhibitor
US Patent:
2006007, Apr 6, 2006
Filed:
Sep 20, 2005
Appl. No.:
11/231470
Inventors:
Heidi Marie Steinfeldt - San Diego CA, US
Theodore James Boritzki - San Diego CA, US
Alan Hilary Calvert - Blaydon-on-Tyne, GB
Nicola Jane Curtin - Rowlands Gill, GB
Mohamed Raza Dewji - Harrow, GB
Zdenek Hostomsky - La Jolla CA, US
Christopher Jones - Gosforth, GB
Rhonda Kaufman - Bridgewater NJ, US
Karen Klamerus - San Diego CA, US
David Richard Newell - Humshaugh, GB
Elizabeth Ruth Plummer - Heddon-on-the-Wall, GB
Steven Reich - Del Mar CA, US
Ian Stratford - Manchester, GB
Huw David Thomas - Houghton-le-Spring, GB
Kay Janine Williams - Middleton, GB
Theodore James Boritzki - San Diego CA, US
Alan Hilary Calvert - Blaydon-on-Tyne, GB
Nicola Jane Curtin - Rowlands Gill, GB
Mohamed Raza Dewji - Harrow, GB
Zdenek Hostomsky - La Jolla CA, US
Christopher Jones - Gosforth, GB
Rhonda Kaufman - Bridgewater NJ, US
Karen Klamerus - San Diego CA, US
David Richard Newell - Humshaugh, GB
Elizabeth Ruth Plummer - Heddon-on-the-Wall, GB
Steven Reich - Del Mar CA, US
Ian Stratford - Manchester, GB
Huw David Thomas - Houghton-le-Spring, GB
Kay Janine Williams - Middleton, GB
International Classification:
A61K 31/55
US Classification:
514212060
Abstract:
This invention generally relates to use of 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one represented by formula 1 as a chemosensitizer that enhances the efficacy of cytotoxic drugs or radiotherapy.
This invention provides pharmaceutical combinations of 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, or a pharmaceutically acceptable salt thereof and at least one additional therapeutic agent, kits containing such combinations and methods of using such combinations to treat subjects suffering from diseases such as cancer.
Karen Klamerus
Location:
Greater San Diego Area
Industry:
Pharmaceuticals