MS. KAREN B. BARRETT, MS, PA-C
Medical Practice in Boise, ID

RE44539, Oct 15, 2013

Mar 20, 2012

13/425181

Vicki S. Thompson - Idaho Falls ID, US
Karen B. Barrett - Meridian ID, US
Diane E. Key - Idaho Falls ID, US

United States Department of Energy - Washington DC

G01N 31/00, G01N 33/53

435 71, 436501, 436518

A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

7682798, Mar 23, 2010

Apr 6, 2005

11/101254

Vicki S. Thompson - Idaho Falls ID, US
Karen B. Barrett - Meridian ID, US
Diane E. Key - Idaho Falls ID, US

Battelle Energy Alliance, LLC - Idaho Falls ID

G01N 33/00, G01N 33/543

435 71, 4351731, 435174, 4352831, 436501, 436518, 422 50, 422 57

A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

7682797, Mar 23, 2010

Apr 6, 2005

11/101216

Vicki S. Thompson - Idaho Falls ID, US
Karen B. Barrett - Meridian ID, US
Diane E. Key - Idaho Falls ID, US

Battelle Energy Alliance, LLC - Idaho Falls ID

G01N 33/00, G01N 33/543

435 71, 436501, 436518, 422 50

A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

6989276, Jan 24, 2006

Dec 14, 2001

10/017577

Vicki S. Thompson - Idaho Falls ID, US
Karen B. Barrett - Meridian ID, US
Diane E. Key - Idaho Falls ID, US

Battelle Energy Alliance, LLC - Idaho Falls ID

G01N 33/543

436518, 436538, 436540, 435 71, 435 792, 435 793, 435971, 435973, 435975, 422 50, 422 56, 422 57, 422 60, 4241301

A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.