JYOTHI S NAMBIAR
Pharmacy in Pittsburgh, PA
License number
Pennsylvania PI094130F
Category
Pharmacy
Type
Pharmacy Intern
Address
Address
Pittsburgh, PA 15217
Professional information
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Directly Compressible Granules Having Improved Flow Properties
Directly Compressible Granules Having Improved Flow Properties
US Patent:
5169645, Dec 8, 1992
Filed:
Oct 31, 1989
Appl. No.:
7/429858
Inventors:
Atul J. Shukla - Memphis TN
Anumontri Vattanasiri - Bangkok, TH
Jyothi S. Nambiar - Pittsburgh PA
Anumontri Vattanasiri - Bangkok, TH
Jyothi S. Nambiar - Pittsburgh PA
Assignee:
Duquesne University Of The Holy Ghost - Pittsburgh PA
International Classification:
A61K 914
US Classification:
424499
Abstract:
Directly compressible, wax-containing granules having improved flow properties are obtained when waxes are admixed in the melt with certain flow improving additives, followed by cooling and granulation of the admixture. In certain embodiments of the invention, only the wax itself melts in the melt combination of the wax(es) and additives(s), and in other cases both the wax(es) and the additives(s) will both melt. In either case, the melt combination of the wax(es) with the additive(s) yields, upon cooling and granulation, a wax-containing particulate drug diluent having improved and unexpected flow properties.