DR. JURRIEN DEAN, M.D.
Osteopathic Medicine at Hampden Ln, Bethesda, MD

License number

Maryland D0022265

Personal information

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Name

Address

Phone

Jurrien Dean, age 77

7422 Hampden Ln, Bethesda, MD 20814

(301) 656-1227

Jurrien Dean

Chevy Chase, MD

(301) 656-1227

Jurrien Dean, age 77

7422 Hampden Ln, Bethesda, MD 20814

(301) 656-1227

Organization information

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Jurrien Dean MD

9000 Rockville Pike, Bethesda, MD 20892

Industry:

Internist

Phone:

(301) 496-6125 (Phone)

Jurrien Dean

National Institutes Of Health - Jurrien Dean MD

9000 Rockville Pike #50-3133, Bethesda, MD 20892

Categories:

Internal Medicine Physicians & Surgeons

Phone:

(301) 496-6125 (Phone)

Professional information

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Jurrien Dean, Bethesda MD

Specialties:

Internal Medicine, Surgery

Work:

National Institutes Of Health
9000 Rockville Pike, Bethesda, MD 20892

Education:

Columbia University (1973)

Dr. Jurrien Dean, Bethesda MD - MD (Doctor of Medicine)

Specialties:

Internal Medicine

Address:

7422 Hampden Ln, Bethesda 20814
(301) 656-1227 (Phone)

Certifications:

Internal Medicine, 1976

Awards:

Healthgrades Honor Roll

Languages:

English

Education:

Medical School
Columbia University / College of Physicians And Surgeons
Graduated: 1973
New York-Presbyterian Hospital
Johns Hopkins

Contraceptive Vaccine Based On Alloimmunization With Zona Pellucida Polypeptides

US Patent:

5916768, Jun 29, 1999

Filed:

May 23, 1997

Appl. No.:

8/862903

Inventors:

Jurrien Dean - Bethesda MD

Assignee:

The United States of America as represented by the Department of Health
and Human Services - Washington DC

International Classification:

C12P 2106, C12N 700, C07H 1900, C07H 1901

US Classification:

435 693

Abstract:

The present invention relates to contraceptive vaccines based on cloned zona pellucida genes and the strategy of alloimmunization with zona pellucida polypeptides. In particular, the present invention relates to a contraceptive vaccine for use in a mammalian female comprising a polypeptide which displays at least one epitope for binding of an antibody that inhibits fertilization of an oocyte by a sperm. This epitope is from a zona pellucida procein of the species in which the said vaccine is used. This invention relates, more particularly, to such vaccines wherein the zona pellucida protein is either the ZP3 or the ZP2 or the ZP1 protein or the mouse or homologues of these proteins in some other mammalian species. Further, this invention comprehends vaccines comprising a synthetic peptide that displays an epitope for such an antibody that inhibits fertilization. In addition, this invention relates to cloned DNA segments variously encoding the mouse ZP3 or ZP2 proteins or the human ZP3 or ZP2 protein.

Contraceptive Vaccine Based On Alloimmunization With Zona Pellucida Polypeptides

US Patent:

5641487, Jun 24, 1997

Filed:

Mar 26, 1993

Appl. No.:

8/038948

Inventors:

Jurrien Dean - Bethesda MD

Assignee:

The Government of the United States of America as represented by the
Secretary Department of Health and Human Services - Washington DC

International Classification:

A61K 3900, A61K 3800, C12P 2104, C07K 200

US Classification:

4241841

Abstract:

The present invention relates to contraceptive vaccines based on cloned zona pellucida genes and the strategy of alloimmunization with zona pellucida polypeptides. In particular, the present invention relates to a contraceptive vaccine for use in a mammalian female comprising a polypeptide which displays at least one epitope for binding of an antibody that inhibits fertilization of an oocyte by a sperm. This epitope is from a zona pellucida protein of the species in which the said vaccine is used. This invention relates, more particularly, to such vaccines wherein the zona pellucida protein is the ZP3 protein or the mouse or homologues of the protein in some other mammalian species. Further, this invention comprehends vaccines comprising a synthetic peptide that displays an epitope for such an antibody that inhibits fertilization. In addition, this invention relates to cloned DNA segments variously encoding the mouse ZP3 protein or the human ZP3 protein.

Contraceptive Vaccine Based On Alloimmunization With Zona Pellucida Polypeptides

US Patent:

5672488, Sep 30, 1997

Filed:

May 30, 1995

Appl. No.:

8/453952

Inventors:

Jurrien Dean - Bethesda MD

Assignee:

The United States of America as represented by the Secretary, Department
of Health and Human Services - Washington DC

International Classification:

C12P 2106, C12N 700, C07H 1900, C07H 1901

US Classification:

435 693

Abstract:

The present invention relates to contraceptive vaccines based on cloned zona pellucida genes and the strategy of alloimmunization with zona pellucida polypeptides. In particular, the present invention relates to a contraceptive vaccine for use in a mammalian female comprising a polypeptide which displays at least one epitope for binding of an antibody that inhibits fertilization of an oocyte by a sperm. This epitope is from a zona pellucida protein of the species in which the said vaccine is used. This invention relates, more particularly, to such vaccines wherein the zona pellucida protein is either the ZP3 or the ZP2 or the ZP1 protein or the mouse or homologues of these proteins in some other mammalian species. Further, this invention comprehends vaccines comprising a synthetic peptide that displays an epitope for such an antibody that inhibits fertilization. In addition, this invention relates to cloned DNA segments variously encoding the mouse ZP3 or ZP2 proteins or the human ZP3 or ZP2 protein.

Contraceptive Vaccine Based On Alloimmunization With Zona Pellucida Polypeptides

US Patent:

5626846, May 6, 1997

Filed:

May 30, 1995

Appl. No.:

8/453472

Inventors:

Jurrien Dean - Bethesda MD

Assignee:

The United States of America as represented by the Department of Health
and Human Services - Rockville MD

International Classification:

A61K 3900, A61K 3800, C12P 2104, C07K 200

US Classification:

4241841

Abstract:

The present invention relates to contraceptive vaccines based on cloned zona pellucida genes and the strategy of alloimmunization with zona pellucida polypeptides. In particular, the present invention relates to a contraceptive vaccine for use in a mammalian female comprising a polypeptide which displays at least one epitope for binding of an antibody that inhibits fertilization of an oocyte by a sperm. This epitope is from a zona pellucida protein of the species in which the said vaccine is used. This invention relates, more particularly, to such vaccines wherein the zona pellucida protein is either the ZP3 or the ZP2 or the ZP1 protein or the mouse or homologues of these proteins in some other mammalian species. Further, this invention comprehends vaccines comprising a synthetic peptide that displays an epitope for such an antibody that inhibits fertilization. In addition, this invention relates to cloned DNA segments variously encoding the mouse ZP3 or ZP2 proteins or the human ZP3 or ZP2 protein.