JUAN C LORENZO
Pharmacy in Miami, FL

2013026, Oct 3, 2013

Mar 30, 2012

13/436430

Juan A. Lorenzo - Davie FL, US

MICRUS ENDOVASCULAR LLC - San Jose CA

A61F 7/12

607113

An embolic coil detachment system includes an elongated, flexible polymer tube having a tubular wall with an inner surface defining an interior lumen. A distal portion of the tubular wall has a score line, and a resistive heating element is located near the score line and in immediate contact with a surface of a distal portion of the tubular wall, to provide direct heating of the distal portion of the flexible polymer tube adjacent to the score line. A therapeutic embolic coil includes a headpiece that is releasably attached within the distal portion of the flexible polymer tube, and that is releasable by heating of the distal portion of the tubular shaft to cause the distal portion of the tubular wall to split along the score line.

2006027, Dec 7, 2006

Jun 30, 2005

11/171679

Vladimir Mitelberg - Aventura FL, US
Donald Jones - Lauderhill FL, US
Juan Lorenzo - Davie FL, US

A61M 29/00

606200000

A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member having a lumen therethrough and being slidably disposed within the lumen of the catheter. A stretch resistant embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member which is attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. The engagement member engages a retaining ring on the embolic device. When the embolic device is advanced to the predetermined site within the vessel, the detachment member is withdrawn from the aperture to thereby release the embolic device at the treatment site.

2013026, Oct 3, 2013

Mar 30, 2012

13/436638

Juan A. Lorenzo - Davie FL, US

MICRUS ENDOVASCULAR LLC - San Jose CA

A61F 2/01

606200

Provided herein are a system and method for detaching a therapeutic device, e.g. an embolic coil, from a delivery tube at a target site in a patient's body. The system includes a bead disposed against a distal end of the therapeutic device that retains the therapeutic device to the delivery tube in a first compressed configuration through a coupling union comprising a series of connectors. The series of connectors may include a stretch resistant member through which the bead is attached to an anchor inside the therapeutic device. The anchor, in turn, may be disposed against a thermally responsive element comprised of a polymeric material configured to melt or otherwise change configuration to release the anchor, and with it, to also release the therapeutic device. Energy may be supplied to the thermally responsive element through electrical conductors and a resistive heating element disposed within the delivery tube.

8313504, Nov 20, 2012

Jun 30, 2005

11/171560

Hiep Q. Do - Hillsborough NJ, US
Donald K. Jones - Lauderhill FL, US
Juan A. Lorenzo - Davie FL, US
Vladimir Mitelberg - Aventura FL, US
Darren R. Sherman - Ft. Lauderdale FL, US
Murty Vyakarnam - South Orange NJ, US

Cordis Corporation - Miami Lakes FL

A61M 29/00

606200

The present invention relates to a medical device for placement at a predetermined location within a passageway of the human body, and more particularly, relates to a flexible embolization device which may be delivered by a catheter to a pre-selected position within a blood vessel to thereby embolize a blood vessel or a blood vessel defect, such as an aneurysm or fistula. Specifically, the embolization device comprises an elongated coil having a lumen, the coil and lumen being at least partially embedded in an elongated foam member comprising, in some embodiments, a flexible, biodegradable, water insoluble, open, interconnecting-cell foam material having embolic characteristics, and capable of allowing cell proliferation into the open cell foam interior.

2009031, Dec 17, 2009

Jun 11, 2008

12/157550

Kirk L. Johnson - Weston FL, US
David A. Kilmer - North Miami FL, US
Juan A. Lorenzo - Davie FL, US
Robert Lulo - Pembroke Pines FL, US

A61B 17/00

606 1

A handle for use with an implantable medical device deployment system that guides and deploys the medical device at a target location within a body vessel. The handle includes a rotatable member, rotation of which causes movement of a control member of the deployment system in an axial direction. An actuator in a handle may include a threaded portion which has at least two different pitch sizes.

2005013, Jun 23, 2005

Jun 15, 2004

10/868303

Donald Jones - Lauderhill FL, US
Juan Lorenzo - Davie FL, US
Mark Pomeranz - Davie FL, US
Darren Sherman - Ft. Lauderdale FL, US

A61M029/00

606200000

A medial device such as a vascular occlusive device which includes a support structure and a bioactive expansible coating disposed on the support structure and an outer barrier coating which serves to prevent a reaction between the bioactive expansible foam coating and bodily fluids until the outer barrier is activated and removed by applying an external agent to the outer barrier thereby permitting expansion of the bioactive foam coating.

2009027, Oct 29, 2009

Dec 12, 2006

12/085885

Kirk L. Johnson - Weston FL, US
Juan A. Lorenzo - Davie FL, US
Robert Lulo - Pembroke Pines FL, US

A61B 19/00

606108

A detachment actuator for use with an implantable medical device deployment system that guide and deploys the medical device at a target location within a body vessel. The detachment actuator includes a first portion that is connected the implantable medical device and a second portion that is attached to a control member the controls the release of the medical device, The second portion of the detachment actuator detaches and moves away from the first portion of the detachment actuator to move the control member and release the medical device.

2006020, Sep 7, 2006

Mar 2, 2005

11/070727

Juan Lorenzo - Davie FL, US
Darren Sherman - Ft. Lauderdale FL, US
Robert Farnan - Davie FL, US
Mark Pomeranz - Davie FL, US

A61M 29/00

606200000

An embolic element may be manufactured by twisting a length of wire about a longitudinal axis thereof, the wire having at least one flat portion along its length, to cause the flat portion to form a generally helical shape. The length of wire is then optionally wound onto a mandrel by bending of the wire to form a three-dimensional shape.

7416757, Aug 26, 2008

Apr 6, 2005

11/100171

Yufu Li - Bridgewater NJ, US
Zhigang Li - Hillsborough NJ, US
Juan A. Lorenzo - Davie FL, US
Murty N. Vyakarnam - South Orange NJ, US

Cordis Neurovascular, Inc. - Miami Lakes FL

B05D 3/12, A61B 1/267, A61B 1/00

427 21, 427 224, 427171, 600200, 600108

A polymeric coating is applied to at least one embolic coil carried in a fixture, at least a portion of said embolic coil being generally vertical and straight. The coil is carried in the fixture during the processing, and may remain in the fixture if desired for further steps of processing.