Inventors:
Eric F. Bernstein - Wynnewood PA
Jouni Uitto - Gladwyne PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
C12N 1500, C12N 1585, A61K 4900, C12Q 100
Abstract:
A transgenic mouse capable of expressing a reporter gene regulated by human elastin promoter is provided. Mouse fibroblast cultures derived from this transgenic mouse are also provided. In addition, methods of identifying compounds capable of inhibiting cutaneous photodamage with this transgenic mouse or fibroblast cultures derived from these mice are provided.