Inventors:
Alfred Liang - Edison NJ, US
Joseph Stauffer - Skillman NJ, US
James Jones - Somerset NJ, US
Assignee:
ALPHARMA, INC. - Bridgewater NJ
International Classification:
A61K 31/485
Abstract:
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided.