Inventors:
Joseph V. DiTrolio - Roseland NJ, US
Assignee:
Boston Scientific Scimed, Inc. - Maple Grove MN
International Classification:
A61K 33/14, A61B 17/42, A61M 5/178, A61M 31/00, A61M 25/06, A61M 5/315
US Classification:
424680, 604 28, 604 36, 604 38, 604 44, 604 48, 604 57, 604 59, 604 60, 604 62, 604 64, 604264, 604272, 606272
Abstract:
Novel methods for the chemical ablation of tissue (e. g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i. e. , about 0. 9%) upon absorption by the body of the subject being treated.