JOSEPH S FRIEDBERG, MD
Radiology in Philadelphia, PA

2010026, Oct 14, 2010

Mar 19, 2008

12/532035

Joseph S. Friedberg - Philadelphia PA, US

A61B 1/00

600114

An endoscopic overtube and method for achieving safe and effective endoscope passage and maintenance of pneumoperitoneum, thereby facilitating natural orifice transluminal endoscopic surgery (NOTES) in a body cavity is provided. The endoscopic overtube is designed to facilitate simultaneous use of at least two endoscopes and includes an sheath that has a proximal portion, a distal portion, and a passageway extending between the proximal portion and the distal portion. A cuff is coupled to the distal portion of the sheath and is inflatable. When the cuff is inflated, a distally facing surface of the cuff contacts an inner lumenal wall, and a proximally facing surface of the cuff contacts an outer peritoneal wall. An inflation lumen is connected to the cuff to deliver inflation fluid to inflate and/or deflate the cuff. A closure device is also provided with the endoscopic overtube for closing an incision in a tissue wall.

2006026, Nov 23, 2006

Jan 17, 2006

11/333805

Joseph Friedberg - Philadelphia PA, US
Shamus Carr - New London CT, US

Thomas Jefferson University - Philadelphia PA

A61B 8/00, A61K 38/00

424009520, 514012000

The present invention is based on the discovery that an increase in systemic oxygenation can be achieved by gastric perfusion of an oxygenated liquid, e.g., perfluorocarbon. Accordingly, the invention provides for a method of treating hypoxia comprising infusing an oxygenated perfluorocarbon fluid into the stomach of the patient for oxygenation throughout the body, and subsequently removing the fluid from the stomach.

2007025, Nov 1, 2007

Apr 20, 2007

11/738106

Joseph S. Friedberg - Philadelphia PA, US

A61B 19/00, A61B 5/08

128898, 600529

A method for repairing pulmonary air leaks in a lung residing in a chest cavity and having an intake air stream and an outer surface is disclosed. An exemplary method comprises: introducing a first component of a biphasic sealant component as a liquid into the intake air stream of the damaged lung; ensuring that there is a pressure differential between the intake air stream and the outer surface of the lung; and introducing a second component of a biphasic sealant component into the chest cavity. The first sealant component collects at the air leak site and forms a sealant in combination with the second sealant component.

2009019, Aug 6, 2009

Feb 6, 2009

12/367068

Joseph Friedberg - Philadelphia PA, US

The Trustees Of The University Of Pennsylvania - Philadelphia PA

A61B 17/08

606151

A device and method for facilitating access to a perimeter surface of a body structure is provided. The device includes an elongate flexible member configured to be positioned adjacent the perimeter surface of the body structure, an atraumatic tip positioned at a distal end of the elongate flexible member, and an elongate body. The elongate body has a surface positioned to guide the elongate flexible member and to permit longitudinal movement of the flexible member with respect to the elongate body. The body also has a curved distal portion and a distal end for releasably engaging the atraumatic tip.

2011030, Dec 15, 2011

Nov 12, 2009

13/129090

Joseph Friedberg - Philadelphia PA, US
Franz Fogt - Gladwyne PA, US

The Trustees of the University of Pennsylvania - Philadelphia PA

G01N 21/75, C12M 1/42, B82Y 15/00

435 725, 4352872, 977700, 977834, 977902, 977890

The present invention provides compositions and methods for the detection of red blood cells antigens. The methods and compositions are based on antibodies, serving as primary antibodies or secondary antibodies, that are labeled with a rare-earth based crystal. Methods utilizing antibodies labeled with a rare-earth based crystal enhance the efficiency and accuracy of blood compatability tests and red blood cells phenotyping.

2010011, May 6, 2010

May 14, 2007

12/300507

Joseph Friedberg - Philadelphia PA, US

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA

A61K 39/00, C12N 13/00, A61P 35/00, A61P 37/04

4242771, 4351731

This invention relates to a vaccine for mesothelioma generated using photodynamic therapy and its use in methods and compositions for treating mesothelioma.