Inventors:
William J. Addicks - Morgantown WV
Joseph P. Duda - Morgantown WV
Daniel A. Snider - Morgantown WV
Kerry R. Benson - Morgantown WV
Assignee:
Mylan Pharmaceuticals Inc. - Morgantown WV
International Classification:
A61K 920
US Classification:
424451, 424464, 424484, 424485, 424486, 424487, 424488, 424469, 514770, 5147723, 514773, 514774, 514777, 514778, 514779, 514781, 514782, 514783
Abstract:
A pharmaceutical composition is provided containing an admixture of phenytoin sodium and an erodible matrix which extends the release of the phenytoin sodium over about a two hour period. The erodible matrix comprises binder(s) and diluent(s) which control the release of drug from the pharmaceutical composition. The erodible matrix can further comprise an alkaline pH modifier.