JOSEPH M MCKINLEY
Physician in Tampa, FL
License number
Florida 7152
Issued Date
Jul 1, 2003
Effective Date
Oct 24, 2005
Expiration Date
Jul 1, 2007
Category
Health Care
Type
Registration for Resident/HSE Physician
Address
Address
PO Box 1289, Tampa, FL 33601
Professional information
Methods Of Detecting And Treating Colon Disorders
US Patent:
2010018, Jul 22, 2010
Filed:
Oct 10, 2009
Appl. No.:
12/577161
Inventors:
WILLIAM G. KERR - Syracuse NY, US
Joseph M. McKinley - Tampa FL, US
Joseph M. McKinley - Tampa FL, US
Assignee:
UNIVERSITY OF SOUTH FLORIDA - Tampa FL
International Classification:
A61K 49/04, A61P 1/00, C12Q 1/02, C12Q 1/68
US Classification:
424 941, 424 94, 435 29, 435 6
Abstract:
The subject invention pertains to a method of detecting colon disorders including inflammatory bowel disease, such as Crohn's disease and ulcerative colitis, based on underexpression of Lipopolysaccharide Responsive Beige-like Anchor (LRBA). Advantageously, the invention may be used to test for inflammatory bowel disease using a blood sample from a subject before a more invasive test for colon disorders is employed. The invention also pertains to methods of treating a colon disorder in a subject in which the colon disorder is detected.