DR. JOSEPH JAMES ZAMBON, D.D.S., PH.D.
Dentist in Buffalo, NY
License number
New York 032559-1
Category
Dentist
Type
Periodontics
Address
Address
3435 Main St Squire Hall, Buffalo, NY 14214
Phone
(716) 829-6006
(716) 688-5506
(716) 688-5506
Personal information
See more information about JOSEPH JAMES ZAMBON at radaris.comName
Address
Phone
133 Presidents Walk, Buffalo, NY 14221
133 Presidents Walk, Williamsville, NY 14221
Professional information
Professor At University At Buffalo
Location:
Buffalo/Niagara, New York Area
Industry:
Higher Education
Experience:
University at Buffalo (Educational Institution; 5001-10,000 employees; Higher Education industry): Professor, (-)
Dr. Joseph J Zambon, Buffalo NY - DDS (Doctor of Dental Surgery)
Specialties:
Periodontics
Address:
3435 Main St, Buffalo 14214
(716) 829-6006 (Phone)
(716) 829-6006 (Phone)
Languages:
English
Monoclonal Antibodies Useful In The Identification Of Microorganisms Causing Periodontal Disease
US Patent:
4741999, May 3, 1988
Filed:
Feb 26, 1986
Appl. No.:
6/833856
Inventors:
Robert J. Genco - Buffalo NY
Joseph J. Zambon - Williamsville NY
Lars A. Christersson - Snyder NY
Mirdza E. Neiders - Amherst NY
Joseph J. Zambon - Williamsville NY
Lars A. Christersson - Snyder NY
Mirdza E. Neiders - Amherst NY
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
C12N 500, C12N 1500, G01N 33569, G01N 33577
US Classification:
435 7
Abstract:
Actinobacillus actinomycetemcomitans has frequently been implicated in juvenile periodontitis. The present monoclonal antibodies are specific to Actinobacillus actinomycetemcomitans. The present monoclonal antibodies are typically employed as reagents which include an inert carrier, preferably a liquid, such as buffered saline solution and a preservative. The carrier compositions are suitably selected to provide for the proper dispersal of bacteria, and to preserve the integrity of antigens and supplemental structures. The selection of the proper carrier is especially important in the detection in mixtures which include bacteria which produce large amounts of autolyltic enzymes such as B. gingivalis. The monoclonal antibodies of the present invention are useful in clinical testing and differentiating antigens in the gingival or subgingival sera.
Detection Of Bacteroides Gingivalis
US Patent:
4994376, Feb 19, 1991
Filed:
May 27, 1987
Appl. No.:
7/054617
Inventors:
Joseph J. Zambon - Williamsville NY
Robert J. Gence - Buffalo NY
Robert J. Gence - Buffalo NY
Assignee:
The Research Foundation of State University of NY - Albany NY
International Classification:
C12Q 137, C12Q 102, C12Q 104, C12N 999
US Classification:
435 24
Abstract:
The present invention relates to the detection of B. gingivalis by the specific ability of B. gingivalis to hydrolyze N-carbobenzoxy-glycyl-glycyl-L-arginine-B-napthylamide derivatives. The present invention also relates to the use of assay systems which inhibit serum amino peptidase and enhance the detection of the B. gingivalis N-CBz-Gly-Gly-Arg peptidase. The assay system inhibits the serum enzyme by the use of a serum aminopeptidase inhibitor which inhibits the activity of serum aminopeptidase to a greater extent that it inhibits the activity of B. gingivalis N-CBz-Gly-Gly-Arg peptidase. The assay system also increases the reliability of detection of the B. gingivalis enzyme by the use of enhancing materials which enhance the enzyme activity of B. gingivalis N-CBz-Gly-Gly-Arg peptidase to a greater extent than such materials enhance the enzyme activity of serum aminopeptidase.
Pharmaceutical Composition For The Treatment Of Periodontitis
US Patent:
4997830, Mar 5, 1991
Filed:
Feb 7, 1990
Appl. No.:
7/476299
Inventors:
Arie J. van Winkelhoff - Houten, NL
Edwin G. Winkel - Amsterdam, NL
Ronald J. Goene - Hoogwoud, NL
Lars A. Christersson - Amherst NY
Joseph J. Zambon - Williamsville NY
Robert J. Genco - Buffalo NY
Edwin G. Winkel - Amsterdam, NL
Ronald J. Goene - Hoogwoud, NL
Lars A. Christersson - Amherst NY
Joseph J. Zambon - Williamsville NY
Robert J. Genco - Buffalo NY
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
A61K 31415, A61K 3143
US Classification:
514197
Abstract:
A pharmaceutical combination of Metronidazole and Amoxicillin for the treatment of periodontitis. Conventional therapeutic doses of both the Metronidazole and Amoxicillin given as a combination therapy has been unexpectedly found to effectively treat periodontitis.