JOSEPH J KARPINSKI
Barber in Pottstown, PA
License number
Pennsylvania BL038452L
Category
Barber Examiners
Type
Barber
Address
Address
Pottstown, PA 19464
Professional information
4,4-(Disubstituted) Cyclohexan-1-One Monomers And Related Compounds
US Patent:
5861421, Jan 19, 1999
Filed:
Jun 23, 1997
Appl. No.:
8/860404
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07D40510, A61K 3144
US Classification:
514338
Abstract:
This invention relates to derivatives of 4,4-(disubstituted)cyclohexan-1-ones and related compounds which are useful for treating allergic and inflammatory diseases.
3,3-(Disubstituted) Cyclohexan-1-Ylidine Acetate Dimers And Related Compounds
US Patent:
5767151, Jun 16, 1998
Filed:
Jun 23, 1997
Appl. No.:
8/605034
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
Joseph M. Karpinski - Pottstown PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31215, A61K 31275, C07C 69708, C07C25537
US Classification:
514525
Abstract:
The present invention relates to novel 3,3-(disubstituted)-cyclohexan-1-ylidene acetate dimers of Formula (I): ##STR1## and related compounds, pharmaceutical compositions containing these compounds, and their use in treating allergic and inflammateory diseases and for inhibiting the production of Tumor Necrosis Factor (TNF).
3,3-(Disubstituted)Cyclohexan-1-One Monomers And Related Compounds
US Patent:
5892098, Apr 6, 1999
Filed:
Apr 15, 1997
Appl. No.:
8/624546
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07C 6976
US Classification:
560 59
Abstract:
This invention relates to derivatives of 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds which are useful for treating allergic and inflammatory diseases.
Method For Synthesis Of Aryl Difluoromethyl Ethers
US Patent:
5731477, Mar 24, 1998
Filed:
Jan 31, 1995
Appl. No.:
8/381165
Inventors:
Joseph M. Karpinski - Pottstown PA
Siegfried B. Christensen - Philadelphia PA
Steven Dabbs - Harlow Essex, GB
Siegfried B. Christensen - Philadelphia PA
Steven Dabbs - Harlow Essex, GB
Assignee:
SmithKline Beecham Corporation - Phila PA
International Classification:
C07C 4976
US Classification:
568663
Abstract:
This invention relates to a method for preparing difluoromethyl ethers, thiols and amines without using chlorofluorocarbon gases. The intermediates prepared by this method can be used to make certain compounds which act as PDE IV inhibitors which are useful for treating asthma and other diseases implicated with the PDE IV isozyme.
4,4-(Disubstituted)Cyclohexan-1-Ol Dimers And Related Compounds
US Patent:
5777176, Jul 7, 1998
Filed:
Jun 23, 1997
Appl. No.:
8/860293
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
Joseph M. Karpinski - Pottstown PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07C22900, C07C 6976, C07C 5900, C07C 5528
US Classification:
568631
Abstract:
The present invention relates to novel dimers of 4. 4-(disubstituted)cyclohexan-1-ol dimers and delated compounds, pharmaceutical compositions containing these compounds, and their use in treating allergic and inflammatory diseases and for inhibiting the production of Tumor Necrosis Factor (TNF).
1,3,3-(Trisubstituted)Cyclohex-1-Ene Dimers And Related Compounds
US Patent:
5795918, Aug 18, 1998
Filed:
Feb 27, 1996
Appl. No.:
8/605182
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
Joseph M. Karpinski - Pottstown PA
Assignee:
SmithKline Beecham Corporation - Phila PA
International Classification:
A01N 4110, A01N 3100, C07C 4100
US Classification:
514709
Abstract:
This invention relates to certain 1,3,3-(trisubstituted)cyclohex-1-ene dimers and related compounds which are useful in treating allergic and inflammatory diseases and for inhibiting the production of Tumor Necrosis Factor (TNF).
1,3,3-(Trisubstituted)Cyclohexanemonomers And Related Compounds
US Patent:
5900417, May 4, 1999
Filed:
Feb 27, 1996
Appl. No.:
8/596244
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07D21302, A61K 3144
US Classification:
514277
Abstract:
This invention relates to certain 1,3,34-(trisubstituted)cyciohexane monomers and related compound which are useful in treating allergic and inflammatory diseases and for inhibiting the production of Tumor Necrosis Factor (TNF).
1, 4, 4-(Trisubstituted) Cyclohex-1-Ene Dimers And Related Compounds
US Patent:
5777160, Jul 7, 1998
Filed:
Jun 23, 1997
Appl. No.:
8/860295
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
Joseph M. Karpinski - Pottstown PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07C22900, C07C 6976, C07C 5900, C07C 5528
US Classification:
562465
Abstract:
This invention relates to certain 1,4,4-(trsubstituted)cyclohex-1-ene dimers and rlated compounds which are useful in treating allergic and inflammatory diseases and for inhibiting the production of Tumor Necrosis Factor (TNF).
4,4-(Disubstituted)Cyclohexan-1-Ols Monomers And Related Compounds
US Patent:
5977122, Nov 2, 1999
Filed:
Dec 2, 1997
Appl. No.:
8/952812
Inventors:
Siegfried B. Christensen - Philadelphia PA
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Joseph M. Karpinski - Pottstown PA
M. Dominic Ryan - Pottstown PA
Paul E. Bender - Cherry Hill NJ
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31505, A61K 31425
US Classification:
514269
Abstract:
The present invention relates to novel 4,4-(disubstituted)cyclohexan-1-ols monomers and related compounds, pharmaceutical compositions containing these compounds, and their use in treating allergic and inflammatory diseases and for inhibiting the production to Tumor necrosis Factor (TNF).
Peptide Deformylase Inhibitors
US Patent:
2013034, Dec 26, 2013
Filed:
Mar 9, 2012
Appl. No.:
14/004105
Inventors:
Kelly M. Aubart - Collegeville PA, US
Andrew B. Benowitz - Collegeville PA, US
Yuhong Fang - Eagleville PA, US
James Hoffman - Ardmore PA, US
Joseph M. Karpinski - Stowe PA, US
Andrew Nicholson Knox - Philadelphia PA, US
Xiangmin Liao - Collegeville PA, US
Donghui Qin - Collegeville PA, US
Dongchuan Shi - Collegeville PA, US
Jared T. Spletstoser - Collegeville PA, US
Andrew B. Benowitz - Collegeville PA, US
Yuhong Fang - Eagleville PA, US
James Hoffman - Ardmore PA, US
Joseph M. Karpinski - Stowe PA, US
Andrew Nicholson Knox - Philadelphia PA, US
Xiangmin Liao - Collegeville PA, US
Donghui Qin - Collegeville PA, US
Dongchuan Shi - Collegeville PA, US
Jared T. Spletstoser - Collegeville PA, US
Assignee:
Glaxosmithkline LLC - Philadelphia PA
International Classification:
C07K 5/078, C07D 401/12, C07D 231/06, C07D 403/12
US Classification:
514 26, 5462754, 514 2191, 514 24, 514 27, 546143, 548195, 548246, 5483561, 544238, 548143, 544131, 546162, 546122, 544329, 548261, 544336, 544317, 544408, 544277, 544324, 514275, 514341, 5483794, 514403, 5142365
Abstract:
The present invention relates to a compound of Formula (I):or
a pharmaceutically acceptable salt thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods directed to bacterial infections and inhibition of bacterial peptide deformylase (PDF) activity.