JOSEPH G MURPHY, M.D.
Osteopathic Medicine at 1 St, Rochester, MN
License number
Minnesota 32465
Category
Osteopathic Medicine
Type
Cardiovascular Disease
Address
Address
200 1St St SW, Rochester, MN 55905
Phone
(507) 284-2511
Professional information
Method For Providing A Restenosis Model In Porcine Coronary Arteries
US Patent:
5304122, Apr 19, 1994
Filed:
Nov 24, 1992
Appl. No.:
7/981959
Inventors:
Robert S. Schwartz - Rochester MN
Joseph G. Murphy - Rochester MN
Rodney G. Wolff - Minnetonka Beach MN
Vincent W. Hull - Ham Lake MN
Joseph G. Murphy - Rochester MN
Rodney G. Wolff - Minnetonka Beach MN
Vincent W. Hull - Ham Lake MN
Assignee:
Medtronic, Inc. - Minneapolis MN
International Classification:
A61M 3100
US Classification:
604 53
Abstract:
A model of arterial restenosis in domestic pigs using deep injury to the coronary arterial media resulting in extensive proliferative response. Metal wire coils are delivered percutaneously to the coronary arteries of pigs with an oversized, high pressure (14 atm) balloon and left in place for 5-6 weeks. During placement, the balloon expands the coils and delivers them securely within the arterial lumen causing fracture of the internal elastic lamina by the coil. An extensive proliferative response occurs and is associated with a lumenal area narrowing of at least 50% Immunohistochemical studies confirms the prominence of smooth muscle cells in the tissue. The histopathologic features of the proliferative response are identical to those observed in cases of restenosis post-angioplasty.
This model closely mimics the proliferative portion of human restenosis both grossly and microscopically. It may thus be useful for understanding human restenosis and for testing therapies aimed at preventing restenosis after balloon angioplasty or other coronary interventional procedures.
Joseph G Murphy, Rochester MN
Specialties:
Cardiologist
Address:
200 1St St Sw, Rochester, MN 55905
Education:
National University of Ireland - Doctor of Medicine
The Mayo Clinic - Fellowship - Cardiology
Mater Misericordiae University Hospital - Residency - Cardiology
Dr. Steevan's Hospital - Dublin (Closed in 1980's) - Residency - Internal Medicine
Beaumont Hospital - Residency - Internal Medicine
The Mayo Clinic - Fellowship - Cardiology
Mater Misericordiae University Hospital - Residency - Cardiology
Dr. Steevan's Hospital - Dublin (Closed in 1980's) - Residency - Internal Medicine
Beaumont Hospital - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine, American Board of Internal Medicine Sub-certificate in Cardiovascular Disease (Internal Medicine)
Dr. Joseph G Murphy, Lakeville MN - MD (Doctor of Medicine)
Specialties:
Cardiology
Address:
FamilyHealth Medical Clinic
9974 214Th St W, Lakeville 55044
(952) 469-0500 (Phone)
Mayo Clinic
200 1St St SW, Rochester 55905
(507) 284-2511 (Phone)
Northfield City Hospital
2000 North Ave, Northfield 55057
(507) 646-1000 (Phone)
9974 214Th St W, Lakeville 55044
(952) 469-0500 (Phone)
Mayo Clinic
200 1St St SW, Rochester 55905
(507) 284-2511 (Phone)
Northfield City Hospital
2000 North Ave, Northfield 55057
(507) 646-1000 (Phone)
Procedures:
Ablation for Treatment of Cardiac Arrythmias, Cardiac Catheterization (incl. Coronary Angiography), Cardiac Imaging, Cardioversion, Elective, Cardioverter-Defibrillator or Pacemaker Insertion, Removal or Repair, Coronary Angioplasty, Atherectomy and Stent
Conditions:
Angina and Acute Coronary Syndrome, Aortic Aneurysm, Aortic Valve Disease, Arrhythmias (incl. Atrial Fibrillation), Cardiomegaly, Cardiomyopathy, Congenital Heart Disease, Congestive Heart Failure, Coronary Artery Disease (CAD), Heart Attack (Acute Myocardial Infarction), Hyperlipidemia, Hypertension, Hypertensive Heart and Chronic Kidney Disease, Hypotension, Marfan Syndrome, Mitral Valve Disease, Pericardial Disease, Pulmonary Hypertension, Tricuspid Valve Disease
Certifications:
Cardiovascular Disease, 2004, Internal Medicine, 1991
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
FamilyHealth Medical Clinic
9974 214Th St W, Lakeville 55044
Northfield City Hospital
2000 North Ave, Northfield 55057
Mayo Clinic
200 1St St SW, Rochester 55905
Mayo Clinic Saint Marys Hospital
1216 2Nd St South #West, Rochester 55902
9974 214Th St W, Lakeville 55044
Northfield City Hospital
2000 North Ave, Northfield 55057
Mayo Clinic
200 1St St SW, Rochester 55905
Mayo Clinic Saint Marys Hospital
1216 2Nd St South #West, Rochester 55902
Education:
Medical School
Royal College Of Surgeons In Ireland, National University Of Ireland, School Of Medicine
Graduated: 1979
Regl Hospital
Graduated: 1980
Dr Stevens Hospital
Graduated: 1984
Mater Hospital
Graduated: 1985
Richmond Hospital
Graduated: 1982
Harvard Med School
Graduated: 1986
Mayo Clinic Rochester
Graduated: 1990
Royal College Of Surgeons In Ireland, National University Of Ireland, School Of Medicine
Graduated: 1979
Regl Hospital
Graduated: 1980
Dr Stevens Hospital
Graduated: 1984
Mater Hospital
Graduated: 1985
Richmond Hospital
Graduated: 1982
Harvard Med School
Graduated: 1986
Mayo Clinic Rochester
Graduated: 1990
Intracatheter Perfusion Pump Apparatus And Method
US Patent:
5092844, Mar 3, 1992
Filed:
Apr 10, 1990
Appl. No.:
7/507155
Inventors:
Robert S. Schwartz - Rochester MN
Joseph G. Murphy - Rochester MN
Joseph G. Murphy - Rochester MN
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
A61M 100
US Classification:
604151
Abstract:
An intracatheter pump apparatus and method is described for infusing fluids through a lumen of a catheter. The intracatheter pump includes a motor or power source on the outside of the catheter which causes movement of a fluid moving mechanism positioned in the lumen of the catheter, the fluid moving mechanism being attached to the distal end of an elongated member which in turn is attached to the motor.
Intracatheter Perfusion Pump Apparatus And Method
US Patent:
5163910, Nov 17, 1992
Filed:
Mar 3, 1992
Appl. No.:
7/845170
Inventors:
Robert S. Schwartz - Rochester MN
Joseph G. Murphy - Rochester MN
Joseph G. Murphy - Rochester MN
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
A61M 100
US Classification:
604151
Abstract:
An intracatheter pump apparatus and method is described for infusing fluids through a lumen of a catheter. The intracatheter pump includes a motor or power source on the outside of the catheter which causes movement of a fluid moving mechanism positioned in the lumen of the catheter, the fluid moving mechanism being attached to the distal end of an elongated member which in turn is attached to the motor.