Inventors:
Lee Techner - Wynnewood PA, US
Maryann Cherubini - Spring City PA, US
Joseph Foss - Gates Mills OH, US
Bruce Wallin - Haverford PA, US
David Jackson - Cape Coral FL, US
Wei Du - Norristown PA, US
William Schmidt - Davis CA, US
Virginia Schmith - Chapel Hill NC, US
Jerry Snidow - Chapel Hill NC, US
Eric Mortensen - Doylestown PA, US
Assignee:
Adolor Corporation - Exton PA
Glaxo Group Limited - Greenford
International Classification:
A61K 31/445
Abstract:
Methods of preventing and treating opioid bowel dysfunction are disclosed. In addition, methods of increasing the frequency of spontaneous complete bowel movements, methods for improving the quality of life of a patient suffering from opioid bowel dysfunction, methods for reducing a patient's dependence on laxatives, and methods for preventing or treating pain are also disclosed.