Inventors:
Joseph Holden - Salt Lake City UT, US
Lester Layfield - Salt Lake City UT, US
International Classification:
C07H 21/04, C12Q 1/68
US Classification:
435006000, 536023100, 536024300, 536024330
Abstract:
The present invention relates to the field of melanoma diagnosis and therapy. In particular, the present invention relates to c-kit activating mutations present in melanoma, and their use for melanoma evaluation and diagnosis, melanoma prognosis, melanoma progression monitoring, and prescribing therapeutic strategies such as treatment with imatinib or other kinase inhibitors.