Inventors:
Irina V. Khanskaya - Morristown NJ, US
Jonathan Sadeh - New York NY, US
Heribeth Staudinger - Green Brook NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 31/366, A61K 31/341, A61P 11/00
Abstract:
Disclosed is a method of treating chronic obstructive disease, said method comprising administering an effective amount of a CXCR2 antagonist and administering an effective amount of at least one drug selected from the group consisting of: angiotensin-converting enzyme inhibitors, Angiotensin II receptor antagonists, cardioselective beta blockers, and lipid regulating drugs. Examples of the CXCR2 antagonist include: (formula 1.0A and 1.0B).