Inventors:
Anthony Harris - Columbia MO, US
Jonathan Thompson - Cincinnati OH, US
Rebecca Rone - Columbia MO, US
Sheila Grant - Columbia MO, US
David Grant - Columbia MO, US
Assignee:
UNIVERSITY OF MISSOURI, OFFICE OF IPA - Columbia MO
International Classification:
A61K 9/14, C07K 1/113, A61P 17/00, C12N 5/071, C12N 5/074, C12N 5/077, C12N 5/079, A61P 19/00, A61K 38/39, C12N 5/0735, B82Y 5/00
US Classification:
424400, 514 171, 530356, 514 172, 435325, 977773, 977906
Abstract:
Disclosed are compositions comprising collagen covalently bound to particles, wherein covalent bonds are formed between reactive groups of the collagen and reactive groups of the particles, and wherein the particles have an average particle diameter ranging from 20 to 1000 nanometers. Also disclosed are various methods that utilize the compositions.