Inventors:
Jonathan O. Martinez - Houston TX, US
Ennio Tasciotti - Houston TX, US
Mikhail Kolonin - Houston TX, US
Mauro Ferrari - Houston TX, US
Assignee:
Board of Regents of the University of Texas System - Austin TX
International Classification:
A61K 35/12, C12N 5/074, C12N 5/0775, C12N 5/0735, C12N 5/0797, A61K 35/30, A61K 35/54, A61P 29/00, A61P 35/00, A61P 17/02, A61K 9/127, A61K 9/70, A61K 49/06, A61K 49/04, A61K 51/06, A61K 49/22, C12N 5/071, B82Y 5/00
US Classification:
424 173, 435325, 435375, 424 937, 424450, 424400, 424 93, 424 94, 424 95, 977773, 977906
Abstract:
The present invention provides modified stem cells that comprise a delivery system that comprises at least one microparticle or nanoparticle, wherein the at least one microparticle or nanoparticle comprises an active agent. The present invention also provides delivery methods that comprise the administration of the modified stem cells to a subject. Additional aspects of the present invention pertain to methods of making said modified stem cells.