JONATHAN J LANGBERG, MD
Osteopathic Medicine at Clifton Rd, Atlanta, GA

6537314, Mar 25, 2003

Jan 30, 2001

09/774869

Jonathan J. Langberg - Atlanta GA
Michael D. Lesh - Mill Valley CA
Erik van der Burg - Sunnyvale CA

ev3 Santa Rosa, Inc. - Santa Rosa CA

A61F 206

623 236, 623 237, 623 111

A mitral annuloplasty and left ventricle restriction device is designed to be transvenously advanced and deployed within the coronary sinus and in some embodiments other coronary veins. The device places tension on adjacent structures, reducing the diameter and/or limiting expansion of the mitral annulus and/or limiting diastolic expansion of the left ventricle. These effects may be beneficial for patients with dilated cardiomyopathy.

6706065, Mar 16, 2004

Jul 19, 2001

09/909193

Jonathan J. Langberg - Atlanta GA
Michael D. Lesh - Mill Valley CA

ev3 Santa Rosa, Inc. - Santa Rosa CA

A61F 206

623 237, 623 236, 623 111, 128898, 600 37

A left ventricle restriction device is designed to be transvenously advanced and deployed within the coronary sinus and in some embodiments other coronary veins. The device places tension on adjacent structures, reducing the diameter and/or limiting diastolic expansion of the left ventricle. This may be beneficial for patients with dilated cardiomyopathy.

6709456, Mar 23, 2004

Oct 1, 2001

09/968272

Jonathan J. Langberg - Atlanta GA
Michael D. Lesh - Mill Valley CA

EV3 Santa Rosa, Inc. - Santa Rosa CA

A61F 206

623 237, 623 236, 128898, 606194

A minimally invasive method of performing mitral annuloplasty is disclosed. An implantable device is positioned within the coronary sinus and tightened around the mitral annulus. Mitral valve regurgitation is monitored before, during, and/or after the tightening step. An on-going drug therapy may be determined, taking into account post-implantation hemodynamic function.

2010006, Mar 18, 2010

May 7, 2009

12/436968

Jonathan Langberg - Atlanta GA, US
Sean Patrick Whalen - Nashville TN, US

EMERGE MEDSYSTEMS, LLC - San Carlos CA

A61N 1/05, A61N 1/362

607 9, 607127

A cardiac stimulation system and method delivers a left ventricle stimulator from a right ventricle lead system in the right ventricle chamber, into a right side of an interventricular septum at a first location, and transmuscularly from the first location to a second location along the left side of the septum. The left ventricle stimulator is affixed at the second location for transmuscular stimulation of the left ventricle conduction system. A biventricular stimulation system further includes a right ventricle stimulator also delivered by the right ventricle lead system to the first location along the right side of the septum for right ventricular stimulation. An energy source is coupled to the transmuscular stimulation system, i.e., a pacemaker, and/or defibrillator, or to enhance contractility, and may be coupled directly or via “leadless” system(s). Various highly beneficial particular arrangements of stimulators and leads are further described.

2008026, Oct 23, 2008

Jan 4, 2008

11/969769

Edwin Langberg - Sanford FL, US
Julia Langberg - Sanford FL, US
Jonathan Langberg - Atlanta GA, US

A61F 7/00

607101

A tissue hyperthermia system and method improves temperature monitoring and control along an energy emitter such as an RF electrode. A two-phase heat transfer system includes a material within an enclosed vessel that is thermally coupled to the electrode. Energizing the electrode to an operating condition emits energy into tissue and heats at least to a threshold temperature wherein the material undergoes a phase transformation within the vessel between a liquid phase and a vapor phase. The phase change assists in cooling, monitoring, and control of emitter temperature. Algorithms estimate maximum temperature either at the emitter or in tissue adjacent the emitter based on monitored parameters at the vessel. Multivariate algorithms use simultaneous power and temperature readings to estimate actual regional temperature, including electrode or tissue hot-spot temperature. A multivariate algorithm is based in particular upon time-dependent aspects of a pulsed RF operating mode. The multi-variate algorithms benefit temperature monitoring and control either together with the two-phase heat transfer system or with other more conventional devices.

2003013, Jul 17, 2003

Jan 3, 2003

10/336311

Jonathan Langberg - Atlanta GA, US
James Peacock - San Carlos CA, US
Michael Lesh - Mill Valley CA, US

A61B018/18

606/041000

The present invention relates to a tissue ablation device assembly which is adapted to form a conduction block along a length of tissue between two predetermined locations along the left atrial wall. The assembly comprises an ablation element on an elongated ablation member that is coupled to each of two delivery members, wherein the delivery members are adapted to controllably position and secure the ablation element along the length of tissue between the predetermined locations. A linear lesion in the tissue between the predetermined locations is then formed by actuation of the ablation element. The invention further provides that the ablation member may slideably engage one or two delivery members such that an adjustable length of the ablation element along the ablation member may be extended externally from the engaged delivery member and along a length of tissue.

6245064, Jun 12, 2001

Jan 11, 2000

9/481089

Michael D. Lesh - Mill Valley CA
Michael Ronald Ross - Hillsborough CA
Jonathan J. Langberg - Atlanta GA
James C. Peacock - Sunnyvale CA

Atrionix, Inc. - Palo Alto CA

A61B 1804

606 34

This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. An equatorial band circumscribes the outer surface of the working length and is adapted to ablate tissue adjacent thereto when actuated by an ablation actuator. The equatorial band has a length relative to the longitudinal axis of the expandable member that is narrow relative to the working length, and is also substantially shorter than its circumference when the working length is in the radially expanded position. A pattern of insulators may be included over an ablation element which otherwise spans the working length in order to form the equatorial band described.

6254599, Jul 3, 2001

Mar 22, 1999

9/273815

Michael D. Lesh - Mill Valley CA
Michael Ronald Ross - Hillsborough CA
Jonathan J. Langberg - Atlanta GA
James C. Peacock - Sunnyvale CA

Atrionix, Inc. - Palo Alto CA

A61B 1818

606 41

This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. An equatorial band circumscribes the outer surface of the working length and is adapted to ablate tissue adjacent thereto when actuated by an ablation actuator. The equatorial band has a length relative to the longitudinal axis of the expandable member that is narrow relative to the working length, and is also substantially shorter than its circumference when the working length is in the radially expanded position. A pattern of insulators may be included over an ablation element which otherwise spans the working length in order to form the equatorial band described.

7988726, Aug 2, 2011

Nov 17, 2003

10/715221

Jonathan J. Langberg - Atlanta GA, US
Michael D. Lesh - Mill Valley CA, US

Edward Lifesciences LLC - Irvine CA

A61F 2/24

623 237

An implantable device is positioned within the coronary sinus and tightened around the mitral annulus to reduce mitral valve regurgitation. The device carries at least one electrode, in electronic communication with a cardiac rhythm management device.