Inventors:
JULIE MCEARCHERN - MILL CREEK WA, US
JONATHAN G. DRACHMAN - SEATTLE WA, US
Assignee:
SEATTLE GENETICS, INC. - BOTHELL WA
International Classification:
A61K 39/395, A61P 35/00
Abstract:
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.