JONATHAN ALAN EPSTEIN
Medical Practice in Delaware
License number
Pennsylvania MD059101L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Delaware
Wayne, PA 19087
Wayne, PA 19087
Personal information
See more information about JONATHAN ALAN EPSTEIN at radaris.comName
Address
Phone
782 N 38Th St, Allentown, PA 18104
821 King Of Prussia Rd, Radnor, PA 19087
821 King Of Prussia Rd, Radnor, PA 19087
121 Belvidere Ave, York, PA 17404
782 N 38Th St, Allentown, PA 18104
Professional information
Predictors Of Transplant Rejection Determined By Peripheral Blood Gene-Expression Profiling
US Patent:
8053182, Nov 8, 2011
Filed:
Jan 31, 2005
Appl. No.:
10/587569
Inventors:
Thomas Cappola - Philadelphia PA, US
Jonathan A. Epstein - Radnor PA, US
Jonathan A. Epstein - Radnor PA, US
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
C12Q 1/68, C12P 19/34, C07H 21/02
US Classification:
435 6, 435 912, 536 231, 536 243
Abstract:
The present invention provides methods and kits for predicting transplant rejection or tolerance. Methods for predicting the probability of cardiac allograft rejection via profiling of peripheral blood gene expression are also provided.
Use Of Hdac And/Or Dnmt Inhibitors For Treatment Of Ischemic Injury
US Patent:
2009010, Apr 23, 2009
Filed:
Nov 30, 2005
Appl. No.:
11/791834
Inventors:
Peter J. Gruber - Swarthmore PA, US
Jonathan A. Epstein - Radnor PA, US
Ibrahim Abdullah - Rigley PA, US
Jonathan A. Epstein - Radnor PA, US
Ibrahim Abdullah - Rigley PA, US
International Classification:
A61K 31/706, C07C 259/06, C07D 221/06, A61P 9/10, C12Q 1/48, C12Q 1/00, C07K 7/54, C07C 311/21
US Classification:
514 43, 562621, 546 97, 530317, 564 86, 435 4, 435 15
Abstract:
The present invention provides methods of ameliorating or reducing the extent of ischemic injury, reperfusion injury, and myocardial infarction, by administering an inhibitor of histone deacetylase enzyme (HDAC) or an inhibitor of DNA methyltransferase enzyme (DNMT).
Use Of Hdac Inhibitors For Treatment Of Cardiac Rhythm Disorders
US Patent:
2010029, Nov 25, 2010
Filed:
May 7, 2008
Appl. No.:
12/599480
Inventors:
Vickas Patel - Havertown PA, US
Jonathan A. Epstein - Radnor PA, US
Jonathan A. Epstein - Radnor PA, US
International Classification:
A61K 38/12, A61K 31/165, A61K 31/19, A61K 31/135, A61P 9/00
US Classification:
514 211, 514619, 514557, 514616, 514646
Abstract:
The present invention provides methods of ameliorating or reducing the extent of cardiac arrhythmia disorders, by administering an inhibitor of histone deacetylase enzyme (HDAC).
Compositions And Methods For Treating Asthma And Other Lung Diseases
US Patent:
2012009, Apr 19, 2012
Filed:
Mar 18, 2010
Appl. No.:
13/256560
Inventors:
Jonathan A. Epstein - Radnor PA, US
Reynold Panettieri - Bensalem PA, US
Reynold Panettieri - Bensalem PA, US
International Classification:
A61K 31/573, A61K 31/167, A61K 31/46, A61P 11/06, A61P 11/08, A61P 11/00, A61P 11/14, A61K 31/165, A61K 31/522
US Classification:
514171, 514575, 514304, 51426334
Abstract:
The present invention provides methods for dilating the bronchi or bronchioles and relaxing a pulmonary smooth muscle in a subject by treating the subject with a pharmaceutical composition, which includes a Histone deacetylase (HDAC) inhibitor. The ability to dilate the bronchi or bronchioles and relax a pulmonary smooth muscle according to the methods of the invention allows treating, alleviating, or inhibiting bronchoconstrictive diseases or disorders and symptoms associated or derived from bronchoconstrictive diseases.