Inventors:
Brian Hoh - Charlestown MA, US
Christopher Ogilvy - Winchester MA, US
Johnny Pryor - Lexington MA, US
Joseph Vacanti - Winchester MA, US
Assignee:
The General Hospital Corporation - Boston MA
International Classification:
A61M 31/00, A61K 35/44
Abstract:
Methods and materials for treating intracranial aneurysms with a tissue-engineered biopolymer are disclosed. A novel technique has been developed which utilizes a tissue-engineering biopolymer (TEBP) with living endothelial cells such that the endothelial cells will produce a neoendothelium across the aneurysm ostium. Alternatively, biocompatible materials can be coated onto aneurysm maintenance devices, and the cells can be seeded onto the biocompatible material.