Inventors:
John S. Lee - Hagerstown MD, US
Peter Pushko - Frederick MD, US
Jonathan F. Smith - Sabillasville MD, US
Robert G. Ulrich - Frederick MD, US
Assignee:
The United States of America as represented by the Secretary of the Army - Washington DC
International Classification:
A01N 43/04, A01N 63/00, A01N 65/00, A61K 48/00, A61K 31/70, C12N 15/00, C12N 15/09, C12N 15/63, C12N 15/70, C12N 15/74, C07H 21/02, C07H 21/04
US Classification:
4353201, 514 44, 424 931, 424 932, 424 936, 536 231, 536 237
Abstract:
Using nucleic acids encoding mutant SEA and SEB exotoxins from , compositions and methods for use in inducing an immune response which is protective against staphylococcal aureus intoxication in subjects is described.