Inventors:
Mary K. Howett - Harrisburg PA
John W. Kreider - Palmyra PA
Assignee:
The Pennsylvania State University - University Park PA
International Classification:
C12Q 170
US Classification:
435 5, 435 11, 435 72, 435 405, 435 4051, 435 4052, 424 91, 424 92, 424422, 424423, 424430, 600 36, 606132, 604 48
Abstract:
A method for screening candidate antimicrobial compounds is described that utilizes a human vaginal xenograft engrafted in a non-human host. The method may be performed by using pathogen inoculated human vaginal xenografts in order to screen a wide range of candidate antimicrobials administered topically or systemically.