JOHN PERFECT, M.D.
Osteopathic Medicine in Durham, NC
License number
North Carolina 24967
Category
Osteopathic Medicine
Type
Infectious Disease
Address
Address
330 Hanes House, Durham, NC 27710
Phone
(919) 620-4467
(919) 684-4016
(919) 684-8902 (Fax)
(919) 684-4016
(919) 684-8902 (Fax)
Personal information
See more information about JOHN PERFECT at radaris.comName
Address
Phone
3533 Mossdale Ave, Durham, NC 27707
Organization information
See more information about JOHN PERFECT at bizstanding.comJohn Perfect MD
200 Trent Dr, Durham, NC 27710
Industry:
Internist
Phone:
(919) 681-6261 (Phone)
Description:
There are 15 doctors at this site. Surgery is not performed at this site.
John Robert Perfect
Professional information
See more information about JOHN PERFECT at trustoria.com
Dr. John Perfect, Durham NC - MD (Doctor of Medicine)
Dr. John Perfect, Durham NC - MD (Doctor of Medicine)
Specialties:
Infectious Disease Medicine
Address:
Durham Office
1 Duke Medical Ctr, Durham 27710
(919) 684-8111 (Phone), (919) 681-8679 (Fax)
Duke Univ Med Ctr Infcts Dis
200 Trent Dr SUITE 1K, Durham 27710
(919) 681-6261 (Phone)
1 Duke Medical Ctr, Durham 27710
(919) 684-8111 (Phone), (919) 681-8679 (Fax)
Duke Univ Med Ctr Infcts Dis
200 Trent Dr SUITE 1K, Durham 27710
(919) 681-6261 (Phone)
Certifications:
Infectious Disease, 1980, Internal Medicine, 1977
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Durham Office
1 Duke Medical Ctr, Durham 27710
Duke Univ Med Ctr Infcts Dis
200 Trent Dr SUITE 1K, Durham 27710
Duke University Hospital
2301 Erwin Rd, Durham 27710
Durham Regional Hospital
3643 North Roxboro Rd, Durham 27704
1 Duke Medical Ctr, Durham 27710
Duke Univ Med Ctr Infcts Dis
200 Trent Dr SUITE 1K, Durham 27710
Duke University Hospital
2301 Erwin Rd, Durham 27710
Durham Regional Hospital
3643 North Roxboro Rd, Durham 27704
Education:
Medical School
University of Toledo
Graduated: 1974
Duke University Med Center
Riverside Methodist Hospital
University Of Mi Hosps and Health Ctrs
University of Toledo
Graduated: 1974
Duke University Med Center
Riverside Methodist Hospital
University Of Mi Hosps and Health Ctrs
Methods Of Combatting Infectious Disease Using Dicationic Bis-Benzimidazoles
Methods Of Combatting Infectious Disease Using Dicationic Bis-Benzimidazoles
US Patent:
5972969, Oct 26, 1999
Filed:
Sep 1, 1998
Appl. No.:
9/145367
Inventors:
Christine C. Dykstra - Chapel Hill NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
Assignee:
The University of North Carolina at Chapel Hill - Chapel Hill NC
Duke University - Durham NC
Gerogia State University Research Foundation, Inc. - Atlanta GA
Duke University - Durham NC
Gerogia State University Research Foundation, Inc. - Atlanta GA
International Classification:
A61K 31445
US Classification:
514338
Abstract:
The present invention provides methods for treating Cryptococcus neoformans and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a dicationic bis-benzimidazole in an amount effective to treat the conditions.
Synthesis And Antimicrobial Activity Of Novel Dicationic “Reversed Amidines”
Synthesis And Antimicrobial Activity Of Novel Dicationic “Reversed Amidines”
US Patent:
7745456, Jun 29, 2010
Filed:
Jul 9, 2007
Appl. No.:
11/825786
Inventors:
David W. Boykin - Atlanta GA, US
Richard R. Tidwell - Pittsboro NC, US
W. David Wilson - Atlanta GA, US
John R. Perfect - Durham NC, US
Chad F. Stephens - Villa Rica GA, US
Richard R. Tidwell - Pittsboro NC, US
W. David Wilson - Atlanta GA, US
John R. Perfect - Durham NC, US
Chad F. Stephens - Villa Rica GA, US
Assignee:
The University of North Carolina at Chapel Hill - Chapel Hill NC
Duke University - Durham NC
Georgia State University Research Foundation, Inc. - Atlanta GA
Duke University - Durham NC
Georgia State University Research Foundation, Inc. - Atlanta GA
International Classification:
A61K 31/435, A61K 43/08, A61K 31/40, A61K 31/38, A61K 31/47, C07D 405/12, C07D 295/04, C07D 333/38, C07D 307/34, C07D 307/02
US Classification:
514277, 514314, 514408, 514438, 514471, 514491, 548577, 549 71, 549472, 549491
Abstract:
The present invention relates to novel 2,5-bis{[alkyl (or aryl) imino] aminophenyl}furans and thiophenes of the general formula.
Methods Of Combating Infectious Diseases Using Dicatoni Bis-Benzimidazoles
Methods Of Combating Infectious Diseases Using Dicatoni Bis-Benzimidazoles
US Patent:
6156779, Dec 5, 2000
Filed:
Jan 4, 2000
Appl. No.:
9/477386
Inventors:
Christine C. Dykstra - Auburn AL
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
Assignee:
University of North Carolina at Chapel Hill - Chapel Hill NC
Duke University - Durham NC
Georgia State University Research Foundation - Atlanta GA
Duke University - Durham NC
Georgia State University Research Foundation - Atlanta GA
International Classification:
A61K 31415
US Classification:
514397
Abstract:
The present invention provides methods for treating Cryptococcus neoformans and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a dicationic bis-benzimidazole in an amount effective to treat the conditions.
Molecular Predictors Of Fungal Infection
Molecular Predictors Of Fungal Infection
US Patent:
2012007, Mar 29, 2012
Filed:
May 26, 2010
Appl. No.:
13/322237
Inventors:
Aimee K. Zaas - Chapel Hill NC, US
Geoffrey S. Ginsburg - Durham NC, US
Joseph Lucas - Chapel Hill NC, US
Hamza Aziz - Durham NC, US
John R. Perfect - Durham NC, US
Geoffrey S. Ginsburg - Durham NC, US
Joseph Lucas - Chapel Hill NC, US
Hamza Aziz - Durham NC, US
John R. Perfect - Durham NC, US
International Classification:
A61K 31/7048, C40B 30/00, C12Q 1/68, A61K 31/4196, A61P 31/00, A61K 31/137, A61K 31/505, A61K 31/343, A61P 31/10, C12Q 1/04, A61K 31/496
US Classification:
514 31, 435 34, 506 7, 435 615, 435 613, 514383, 51425407, 514654, 514274, 514462
Abstract:
Methods for identifying fungal infection, assays for identifying genomic and protein markers of fungal infection, and methods for diagnosing the fungal infection. In one aspect, the method of identifying fungal infection by proteomic assay involves measuring the protein levels of proteins listed in Table 2A in a peripheral blood cell sample and comparing the determined protein levels to standard protein levels. In another aspect, subjects identified as being infected with fungal infection are treated with anti-fungals.
Method Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
Method Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
US Patent:
6017941, Jan 25, 2000
Filed:
Sep 1, 1998
Appl. No.:
9/145368
Inventors:
Christine C. Dykstra - Chapel Hill NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
Assignee:
The University of North Carolina at Chapel Hill - Chapel Hill NC
Duke University - Durham NC
Georgia State University Research Foundation - Atlanta GA
Duke University - Durham NC
Georgia State University Research Foundation - Atlanta GA
International Classification:
A61K 31415
US Classification:
514394
Abstract:
The present invention provides methods for treating Cryptococcus neoformans and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a dicationic bis-benzimidazole in an amount effective to treat the conditions.
Method Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
Method Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
US Patent:
5643935, Jul 1, 1997
Filed:
Jun 7, 1995
Appl. No.:
8/472996
Inventors:
Christine C. Dykstra - Chapel Hill NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
Assignee:
The University of North Carolina at Chapel Hill - Chapel Hill NC
Duke University - Durham NC
Georgia State University Research Foundation, Inc. - Atlanta GA
Duke University - Durham NC
Georgia State University Research Foundation, Inc. - Atlanta GA
International Classification:
A61K 31505
US Classification:
514394
Abstract:
The present invention provides methods for treating Cryptococcus neoformans and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a dicationic bis-benzimidazole in an amount effective to treat the conditions.
Methods Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
Methods Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
US Patent:
5639755, Jun 17, 1997
Filed:
May 1, 1996
Appl. No.:
8/641510
Inventors:
Christine C. Dykstra - Chapel Hill NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
Assignee:
University of North Carolina - Chapel Hill NC
Duke University - Durham NC
Georgia State Univ. Research Foundation - Atlanta GA
Duke University - Durham NC
Georgia State Univ. Research Foundation - Atlanta GA
International Classification:
A61K 31505
US Classification:
514256
Abstract:
The present invention provides methods for treating Cryptococcus neoformans and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a dicationic bis-benzimidazole in an amount effective to treat the conditions.
Methods Of Treating Microbial Infections
Methods Of Treating Microbial Infections
US Patent:
5668167, Sep 16, 1997
Filed:
Jun 7, 1995
Appl. No.:
8/477876
Inventors:
Richard R. Tidwell - Pittsboro NC
James E. Hall - Chapel Hill NC
David W. Boykin - Atlanta GA
Christine C. Dykstra - Chapel Hill NC
John Perfect - Durham NC
Byron L. Blagburn - Auburn AL
James E. Hall - Chapel Hill NC
David W. Boykin - Atlanta GA
Christine C. Dykstra - Chapel Hill NC
John Perfect - Durham NC
Byron L. Blagburn - Auburn AL
Assignee:
Duke University - Durham NC
Auburn University - Auburn AL
Georgia State University - Atlanta GA
The University of North Carolina at Chapel Hill - Chapel Hill NC
Auburn University - Auburn AL
Georgia State University - Atlanta GA
The University of North Carolina at Chapel Hill - Chapel Hill NC
International Classification:
A61K 3140
US Classification:
514411
Abstract:
The present invention provides methods for treating Cryptococcus neoformans, Cryptosporidium parvum, and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a compound of Formula I: ##STR1## wherein: X is located in the para or meta positions and is loweralkyl, loweralkoxy, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, alkylaryl, halogen, or ##STR2## wherein: each R. sub. 2 is independently selected from the group consisting of H, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl or two R. sub. 2 groups together represent C. sub. 2 -C. sub. 10 alkylene, or two R. sub. 2 groups together represent ##STR3## wherein m is from 1-3 and R. sub. 4 is H, ##STR4## or --CONHR. sub. 5 NR. sub. 6 R. sub.
Methods Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
Methods Of Combatting Infectious Diseases Using Dicationic Bis-Benzimidazoles
US Patent:
5792782, Aug 11, 1998
Filed:
May 29, 1997
Appl. No.:
8/865424
Inventors:
Christine C. Dykstra - Chapel Hill NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
John Perfect - Durham NC
David W. Boykin - Atlanta GA
W. David Wilson - Atlanta GA
Richard R. Tidwell - Pittsboro NC
Assignee:
The University of North Carolina at Chapel Hill - Chapel Hill NC
Duke University - Durham NC
Georgia State University Research Foundation, Inc. - Atlanta GA
Duke University - Durham NC
Georgia State University Research Foundation, Inc. - Atlanta GA
International Classification:
A61K 31415
US Classification:
514394
Abstract:
The present invention provides methods for treating Cryptococcus neoformans and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a dicationic bis-benzimidazole in an amount effective to treat the conditions.