DR. JOHN PATRICK HANRAHAN, M.D
Osteopathic Medicine at Grayfield Ave, Boston, MA

2012010, May 3, 2012

Mar 26, 2010

13/259651

Michael M. Lipp - Framingham MA, US
Robert W. Clarke - Medfield MA, US
David L. Hava - Natick MA, US
Richard Batycky - Newton MA, US
John Hanrahan - West Roxbury MA, US

Pulmatrix, Inc. - Lexington MA

A61K 33/42, A61K 33/10, A61K 33/06, A61K 33/00, A61K 33/04, A61K 33/22, A61K 31/19, A61K 31/734, A61K 31/20, A61K 31/191, A61K 31/194, A61K 31/375, A61K 31/192, A61P 31/00, A61K 33/14

424602, 424678, 424687, 424696, 424680, 424717, 424715, 424709, 424606, 424711, 424660, 424600, 514557, 514 54, 514558, 514574, 514474, 514568

The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Cato Na is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.

2011025, Oct 13, 2011

Oct 22, 2009

13/125506

Holly Huang - Northborough MA, US
Elizabeth B. Goodwin - Upton MA, US
Kendyl M. Schaefer - Dedham MA, US
John P. Hanrahan - West Roxbury MA, US
William T. Andrews - Hopkinton MA, US
Paul Mcglynn - Northborough MA, US

SUNOVION PHARMACEUTICALS INC. - Marlborough MA

A61K 9/00, A61P 11/06, A61P 11/08, A61K 31/439, A61P 11/00

424400, 514291

Compositions and methods for the prevention and/or treatment of airway and/or respiratory disorders are provided. The compositions comprise arformoterol (the (R,R)-formoterol isomer) and tiotropium.

2012005, Mar 8, 2012

Mar 26, 2010

13/259615

Robert W. Clarke - Medfield MA, US
Richard Batycky - Newton MA, US
Wesley H. Dehaan - Chelmsford MA, US
David L. Hava - Natick MA, US
Michael M. Lipp - Framingham MA, US
John Hanrahan - West Roxbury MA, US

PULMATRIX, INC. - Lexington MA

A61P 31/04, A61K 33/06, A61K 33/14

424602, 424680, 424682, 424687, 514557

The invention relates to methods for treating bacterial infection of the respiratory tract, including pneumonias, such as ventilator-associated pneumonia, and to methods for treating ventilator-associated tracheobronchitis, comprising administering an effective amount of a salt formulation as an aerosol to the respiratory tract of an individual in need thereof. The formulations can also be used to reduce transmission of pathogen which can infect the respiratory tract, cause pneumonia or cause ventilator-associated tracheobronchitis.