Inventors:
John M. Amatruda - New York NY, US
Tung M. Fong - Somerset NJ, US
David E. Moller - Bedminster NJ, US
Nancy A. Thornberry - Westfield NJ, US
Assignee:
MERCK & CO., INC. - Rahway NJ
International Classification:
A61K 31/4985, A61P 3/06, A61P 3/10
Abstract:
The present invention relates to pharmaceutical compositions comprising a combination of a particular dipeptidyl peptidase-IV (DPP-IV) inhibitor and a particular cannabinoid CB?1#191 receptor antagonist/inverse agonist, kits containing such combinations and methods of using such compositions for the treatment of diabetes, diabetes associated with obesity, diabetes-related disorders, obesity, and obesity-related disorders.