Inventors:
Robert N. HOTCHKISS - Riverside CT, US
John A. Koski - New York NY, US
Assignee:
Hospital for Special Surgery - New York NY
International Classification:
A61M 5/00, A61K 9/00, A61K 31/573, A61P 29/00, A61K 31/7036, A61K 31/445, A61P 31/04, A61K 38/18
US Classification:
604175, 424423, 514180, 514 40, 514330, 514 81, 604 9301
Abstract:
A drug delivery device may include a base to be percutaneously affixable in an attachment zone of a synovial joint and a sustained-release drug carrier coupled to the base. The drug delivery device may also include an access device to provide access to the attachment zone. The attachment zone may comprise a non-articulating portion of a bone and/or cartilage with the synovial joint and the drug carrier may elute the drug into the synovial fluid sufficient to sustain a therapeutically effective concentration of the drug in the synovial fluid for at least 8 hours.