JOHN J CURRAN
Broker in Worcester, MA
License number
Massachusetts 54587
Issued Date
Sep 1, 1966
Expiration Date
Apr 19, 1992
Type
Broker
Address
Address
Worcester, MA 01609
Professional information
Compositions And Methods For Genetic Analysis Of Polycystic Kidney Disease
US Patent:
6916619, Jul 12, 2005
Filed:
Feb 26, 2002
Appl. No.:
10/083246
Inventors:
Jeffrey George Jones - Wilbraham MA, US
Aidan Noel Hennigan - Millbury MA, US
John A. Curran - Worcester MA, US
Susan Kimberly Allen - Worcester MA, US
Normand J. Robichaud - Leominster MA, US
Jing Wang - Worcester MA, US
Kerry Ellen Flynn - Grafton MA, US
Jorge A. Garcés - Dudley MA, US
Christopher M. Palatucci - Shrewsbury MA, US
Aidan Noel Hennigan - Millbury MA, US
John A. Curran - Worcester MA, US
Susan Kimberly Allen - Worcester MA, US
Normand J. Robichaud - Leominster MA, US
Jing Wang - Worcester MA, US
Kerry Ellen Flynn - Grafton MA, US
Jorge A. Garcés - Dudley MA, US
Christopher M. Palatucci - Shrewsbury MA, US
Assignee:
Athena Diagnostics, Inc. - Worcester MA
International Classification:
C12Q001/68
US Classification:
435 6, 435 911, 435 912
Abstract:
The subject invention relates to methods for detection of mutations in a PKD gene using DHPLC. The invention includes the following aspects: identification of PKD unique sites; design of PKD-specific primers; amplification of PKD-specific products; and analysis of PCR amplified products by DHPLC. The invention further relates to compositions such as identified unique sites and PKD-specific primers, and kits for performing the methods of the invention.
Compositions And Methods For Genetic Analysis Of Polycystic Kidney Disease
US Patent:
7273701, Sep 25, 2007
Filed:
Apr 11, 2003
Appl. No.:
10/411915
Inventors:
Jeffrey G. Jones - Wilbraham MA, US
Aidan N. Hennigan - Millbury MA, US
John A. Curran - Worcester MA, US
Susan K. Allen - Worcester MA, US
Normand J. Robichaud - Leominster MA, US
Jing Wang - Worcester MA, US
Kerry E. Flynn - Grafton MA, US
Jorge A. Garcés - Dudley MA, US
Christopher M. Palatucci - Shrewsbury MA, US
William K. Seltzer - Holden MA, US
Aidan N. Hennigan - Millbury MA, US
John A. Curran - Worcester MA, US
Susan K. Allen - Worcester MA, US
Normand J. Robichaud - Leominster MA, US
Jing Wang - Worcester MA, US
Kerry E. Flynn - Grafton MA, US
Jorge A. Garcés - Dudley MA, US
Christopher M. Palatucci - Shrewsbury MA, US
William K. Seltzer - Holden MA, US
Assignee:
Athena Diagnostics, Inc. - Worcester MA
International Classification:
C12Q 1/68, C12P 19/34
US Classification:
435 6, 435 911, 435 912
Abstract:
The subject invention relates to nucleic acid sequences for detection of mutations in a PKD-1 or PKD-2 gene, as well as biomarkers for ADPKD. The invention further relates to methods for diagnosing ADPKD in an individual, and kits for performing the methods of the invention. The invention also provides a method for determining in an individual the presence or absence of a mutant PKD gene.
Compositions And Methods For Genetic Analysis Of Polycystic Kidney Disease
US Patent:
7521190, Apr 21, 2009
Filed:
Mar 2, 2007
Appl. No.:
11/713772
Inventors:
Jeffrey G. Jones - Wilbraham MA, US
Aidan N. Hennigan - Millbury MA, US
John A. Curran - Worcester MA, US
Susan K. Allen - Worcester MA, US
Normand J. Robichaud - Leominster MA, US
Jing Wang - Worcester MA, US
Kerry E. Flynn - Grafton MA, US
Jorge A. Garcés - Dudley MA, US
Christopher M. Palatucci - Shrewsbury MA, US
William K. Seltzer - Holden MA, US
Aidan N. Hennigan - Millbury MA, US
John A. Curran - Worcester MA, US
Susan K. Allen - Worcester MA, US
Normand J. Robichaud - Leominster MA, US
Jing Wang - Worcester MA, US
Kerry E. Flynn - Grafton MA, US
Jorge A. Garcés - Dudley MA, US
Christopher M. Palatucci - Shrewsbury MA, US
William K. Seltzer - Holden MA, US
Assignee:
Athena Diagnostics, Inc. - Worcester MA
International Classification:
C12Q 1/68, C12P 19/34
US Classification:
435 6, 435 912
Abstract:
The subject invention relates to nucleic acid sequences for detection of mutations in a PKD-1 or PKD-2 gene, as well as biomarkers for ADPKD. The invention further relates to methods for diagnosing ADPKD in an individual, and kits for performing the methods of the invention. The invention also provides a method for determining in an individual the presence or absence of a mutant PKD gene.