JOHN HOLT
Cosmetology in Philadelphia, PA
License number
Pennsylvania CO197574L
Category
Cosmetology
Type
Cosmetologist
Address
Address
Philadelphia, PA 19152
Professional information
John Holt
Location:
Greater Philadelphia Area
Industry:
Information Technology and Services
John Holt - Philadelphia, PA
Work:
Globe
Shipping and Receiving Clerk
Shipping and Receiving Clerk
John Holt - Philadelphia, PA
Work:
Larkin's Family Restaurant - Wildwood, NJ
Dishwasher Shoprite - Philadelphia, PA
Cart Attendant Keenan's Bar - Wildwood, NJ
Clean-up Crew
Dishwasher Shoprite - Philadelphia, PA
Cart Attendant Keenan's Bar - Wildwood, NJ
Clean-up Crew
Trigramin - A Platelet Aggregation Inhibiting Polypeptide
US Patent:
5066592, Nov 19, 1991
Filed:
Sep 19, 1990
Appl. No.:
7/584820
Inventors:
Tur-Fu Huang - Taipei, TW
Stefan Niewiarowski - Narberth PA
John C. Holt - Philadelphia PA
Hanna Lukasiewicz - Warsaw, PL
Stefan Niewiarowski - Narberth PA
John C. Holt - Philadelphia PA
Hanna Lukasiewicz - Warsaw, PL
Assignee:
Temple University of the Commonwealth System of Higher Education - Philadelphia PA
International Classification:
C12N 508, A61K 3702, C07K 710, C07K 1508
US Classification:
4352402
Abstract:
Trigramin, a 72-amino acid polypeptide, has the following amino acid sequence: EAGEDCDCGSPANPCCDAATCKLIPGAQCGEGLCCDQCSFIEEGTVCRIARGDDLDDYCNGRSAGCPRNPFH. The molecule is a potent inhibitor of fibrinogen binding to receptors expressed on the glycoprotein IIb/IIIa complex in the membrane of platelets. Trigramin is thus a potent inhibitor of fibrinogen-induced human platelet aggregation. It is useful in inhibiting the formation of hemostatic platelet plugs.
John Holt
Location:
Greater Philadelphia Area
Industry:
Electrical/Electronic Manufacturing