DR. JOHN HERBERT GROWDON, MD
Neurology at Parkman St, Boston, MA

License number
Massachusetts 0023371
Category
Neurology
Type
Neurology
Address
Address
15 Parkman St, Boston, MA 02114
Phone
(617) 726-1728
(617) 726-4101 (Fax)
(617) 724-0287
(617) 726-2894 (Fax)

Professional information

John Herbert Growdon Photo 1

John Herbert Growdon, Boston MA

Specialties:
Neurologist
Address:
15 Parkman St, Boston, MA 02114
Education:
University of Pennsylvania, Perelman School of Medicine - Doctor of Medicine
Massachusetts General Hospital - Residency - Neurology
Bernard Mitchell Hospital-University of Chicago Hospitals - Residency - Internal Medicine
Board certifications:
American Board of Psychiatry and Neurology Certification in Neurology (Psychiatry and Neurology)


John H Growdon Photo 2

Dr. John H Growdon, Boston MA - MD (Doctor of Medicine)

Specialties:
Neurology
Address:
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St, Boston 02114
(617) 726-8709 (Phone), (617) 724-3948 (Fax)
Massachusetts General Memory
15 Parkman St STE 835, Boston 02114
(617) 726-1728 (Phone)
Certifications:
Neurology, 1982
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
MASSACHUSETTS GENERAL HOSPITAL
15 Parkman St, Boston 02114
Massachusetts General Memory
15 Parkman St STE 835, Boston 02114
Massachusetts General Hospital
55 Fruit St, Boston 02114
Education:
Medical School
University Of Pennsylvania School Of Medicine
Graduated: 1965
University Chicago Hosps
Graduated: 1966
Massachusetts General Hospital
Graduated: 1974
Graduated: 1969
Mass Institute Tech
Graduated: 1977


John Growdon Photo 3

Antemortem Diagnostic Test For Alzheimer's Disease

US Patent:
5631168, May 20, 1997
Filed:
Dec 12, 1994
Appl. No.:
8/353960
Inventors:
John H. Growdon - Chestnut Hill MA
Roger M. Nitsch - Boston MA
Richard J. Wurtman - Boston MA
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
G01N 3392
US Classification:
436 71
Abstract:
An antemortem diagnostic test for neurodegenerative disease, particularly Alzheimer's disease, is disclosed. The method of the invention involves the collection of a sample of bodily fluid; the analysis of the concentration of neuronal membrane phospholipids and phospholipid metabolites, or the ratio of a phospholipid to its metabolite, in the sample; and the correlation of the concentration or the ratio to the corresponding value from control samples. The method can be used to determine the presence or the possibility that an individual can develop a neurodegenerative disease, such as Alzheimer's disease; to follow the course of neurodegenerative disease in an individual; and to validate the efficacy of a drug used to treat a neurodegenerative disease.


John Growdon Photo 4

Methods Of Identifying Agents Which Regulate Release Of Amyloid Precursor Protein

US Patent:
6329155, Dec 11, 2001
Filed:
Apr 15, 1994
Appl. No.:
8/228078
Inventors:
Roger M. Nitsch - Boston MA
Barbara E. Slack - Cambridge MA
Richard J. Wurtman - Boston MA
John H. Growdon - Chestnut Hill MA
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
G01N 33567, G01N 3353, C12P 2106
US Classification:
435 721
Abstract:
Amyloid precursor protein (APP) processing which is activated by cell-surface neurotransmitter receptors, is described. An assay for testing an agent for the capacity to regulate, and particularly to stimulate, secretion of amyloid precursor protein (APP), a description of the characteristics of agents identified by the assay, and a method of altering APP processing in an individual are also disclosed. The assay, agents, and method of altering APP processing are particularly useful for the treatment and prevention of diseases involving APP processing, such as Alzheimer's disease.