Inventors:
Todd Sacktor - Yonkers NY, US
John Crary - New York NY, US
Alejandro Hernanadez - Queens NY, US
Suzanme Mirra - Brooklyn NY, US
Charles Shao - Forest Hills NY, US
International Classification:
A01K 67/027, G01N 33/567, A61K 39/395
US Classification:
800012000, 435007200, 530388260, 424146100
Abstract:
The present invention establishes a link between altered aPKC function and nervous system disorders and cancers, such as Alzheimer's disease (AD) and neuroblastoma. Methods of using aPKC in diagnosis, drug screening and gene therapy in nervous system disorders and cancers are provided.