JOHN CHAE, MD, ME
Physical Therapy at Metrohealth Dr, Cleveland, OH

8165685, Apr 24, 2012

Sep 28, 2006

11/536495

Jayme S. Knutson - Mentor OH, US
John Chae - Strongsville OH, US

Case Western Reserve University - Cleveland OH

A61N 1/00

607 48, 607 2

A system for neuromuscular electrical stimulation therapy includes one or more sensors for sensing the position or the muscle contractions of a body part, such as an arm, hand, finger, leg, etc. ; a stimulator in communication with the sensor or sensors; and two or more electrodes that can be positioned to activate the paralyzed body part. Based on signals from the one or more sensors, the stimulator can regulate the stimulation provided through the electrodes, including the intensity and duration of the electrical stimulation signal. The sensors can be assembled in a wearable article, such as a glove, sock, or sleeve, to monitor the position or muscle contractions of the healthy body part. The electrodes also may be assembled in a wearable device that allows customized placement of those electrodes.

2013025, Sep 26, 2013

Mar 8, 2013

13/791710

Joseph W. Boggs - Carrboro NC, US
Amorn Wongsarnpigoon - Morrisville NC, US
John Chae - Strongsville OH, US
Warren P. Grill - Chapel Hill NC, US
Kathryn Stager - University Heights OH, US
Rosemary Zang - Avon Lake OH, US

SPR THERAPEUTICS, LLC - Cleveland OH

A61N 1/36

607 46

It has been discovered that pain felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. A method has been developed to reduce pain in a painful region following limb joint replacement by stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following total knee arthroplasty surgery or other limb joint replacement surgeries.

2012031, Dec 6, 2012

Dec 1, 2011

13/309024

Maria E. BENNETT - Beachwood OH, US
Warren M. GRILL - Chapel Hill OH, US
John CHAE - Strongsville OH, US

SPR THERAPEUTICS, LLC - Cleveland OH

A61N 1/04

607115

Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

2012031, Dec 6, 2012

Dec 1, 2011

13/309152

Maria E. Bennett - Beachwood OH, US
Warren M. Grill - Chapel Hill OH, US
John Chae - Strongsville OH, US

SPR THERAPEUTICS, LLC - Cleveland OH

A61N 1/36, A61N 1/04

607 46, 607115

Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

2012031, Dec 6, 2012

Dec 1, 2011

13/309107

MARIA E. BENNETT - BEACHWOOD OH, US
WARREN M. GRILL - CHAPEL HILL OH, US
JOHN CHAE - STRONGSVILLE OH, US

SPR THERAPEUTICS, LLC - CLEVELAND OH

A61N 1/36, A61N 1/04

607 46, 607115

Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

8626302, Jan 7, 2014

Aug 3, 2009

12/462371

Maria E. Bennett - Beachwood OH, US
Geoffrey B. Thrope - Shaker Heights OH, US
Andreas Inmann - Cleveland OH, US
John Chae - Strongsville OH, US

SPR Therapeutics, LLC - Cleveland OH

A61N 1/04

607 46, 607 48

Systems and methods are adapted to provide the relief of pain. The systems and methods make possible the percutaneous placement of one or more intramuscular leads, without the need for fluoroscopy, for providing electrical stimulation to activate a motor point innervating the muscle, to provide the therapeutic relief of pain. The one or more intramuscular leads may be placed in muscle(s) to resist migration. The target nerves and their motor points innervate the muscles in which the one or more leads are placed. The systems and methods can include a two-stage solution. The first stage may include temporary systems and methods, including the use of an external pulse generator. The second stage may include more permanent systems and methods, including the use of an implanted pulse generator.

2014004, Feb 13, 2014

Dec 5, 2011

13/991033

Maria E. Bennett - Beachwood OH, US
John Chae - Strongsville OH, US

SPR Therapeutics, LLC - Cleveland OH

A61N 1/05

607116

Systems and methods are provided for treating chronic pain occurring secondarily to subacromial impingement syndrome in a human body. A system is provided to deliver percutaneous electrical stimulation through at least one electrode to neurological motor points of the posterior and middle deltoid muscles to mediate such pain. One-time, continued and/or periodic dosing of treatment methods according to the present invention may result in a change to central nervous system maladaptive neuroplasticity.