John C Fraser, III
Engineers at Sorrento Vly Rd, San Diego, CA
License number
Colorado 26834
Issued Date
Feb 26, 1990
Renew Date
Nov 1, 2015
Expiration Date
Oct 31, 2017
Type
Professional Engineer
Address
Address
11772 Sorrento Valley Rd SUITE 234, San Diego, CA 92121
Professional information
Methods Of Using Regenerative Cells In The Treatment Of Peripheral Vascular Disease And Related Disorders
US Patent:
2009029, Dec 3, 2009
Filed:
Jun 29, 2009
Appl. No.:
12/494211
Inventors:
John K Fraser - San Diego CA, US
Marc H Hedrick - Encinitas CA, US
Eric Daniels - Encinitas CA, US
Marc H Hedrick - Encinitas CA, US
Eric Daniels - Encinitas CA, US
International Classification:
A61K 35/12
US Classification:
424 9321, 424 937
Abstract:
Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
Methods Of Using Adipose Tissue-Derived Cells In The Treatment Of Cardiovascular Conditions
US Patent:
2009026, Oct 29, 2009
Filed:
Mar 30, 2009
Appl. No.:
12/414582
Inventors:
John K. Fraser - San Diego CA, US
Marc H. Hedrick - Encinitas CA, US
Min Zhu - San Diego CA, US
Brian M. Strem - San Diego CA, US
Eric Daniels - Encinitas CA, US
Isabella Wulur - Rancho Cucamonga CA, US
Marc H. Hedrick - Encinitas CA, US
Min Zhu - San Diego CA, US
Brian M. Strem - San Diego CA, US
Eric Daniels - Encinitas CA, US
Isabella Wulur - Rancho Cucamonga CA, US
International Classification:
A61K 35/12
US Classification:
424 937
Abstract:
Cells present in processed lipoaspirate tissue are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.
Methods Of Using Regenerative Cells In The Treatment Of Stroke And Related Diseases And Disorders
US Patent:
2012030, Dec 6, 2012
Filed:
Aug 15, 2012
Appl. No.:
13/586735
Inventors:
John K. Fraser - San Diego CA, US
Marc H. Hedrick - Encinitas CA, US
Brian M. Strem - Encinitas CA, US
Marc H. Hedrick - Encinitas CA, US
Brian M. Strem - Encinitas CA, US
Assignee:
CYTORI THERAPEUTICS, INC. - San Diego CA
International Classification:
A61K 35/12, A61K 38/20, A61P 9/00
US Classification:
424 852, 424 937
Abstract:
Cells present in adipose tissue are used to stroke and stroke related diseases and disorders in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
Methods Of Using Adipose Tissue-Derived Cells In The Treatment Of The Lymphatic System And Malignant Disease
US Patent:
2011020, Aug 25, 2011
Filed:
Feb 18, 2011
Appl. No.:
13/031031
Inventors:
Zeni Alfonso - Temecula CA, US
John K. Fraser - San Diego CA, US
John K. Fraser - San Diego CA, US
International Classification:
A61K 35/12, A61P 3/06, A61P 9/00, A61P 35/04
US Classification:
424 937
Abstract:
Aspects of the invention provides methods for preparing and using adipose-tissue-derived stem and progenitor cells, adipose-tissue-derived lymphatic endothelial cells, and cells capable of differentiating into lymphatic endothelial cells to treat disorders of the lymphatic system and to modulate expansion, repair, and/or regeneration of the lymphatic system. The invention further provides using adipose-tissue-derived lymphatic endothelial cells and cells capable of differentiating into lymphatic endothelial cells for delivery of therapeutic agents to tumor cells as a means for treating malignant disease, and assays to screen for drugs that modulate lymphatic system expansion, repair or regeneration.
Methods Of Making Enhanced, Autologous Fat Grafts
US Patent:
7901672, Mar 8, 2011
Filed:
Sep 20, 2010
Appl. No.:
12/886353
Inventors:
John K. Fraser - San Diego CA, US
Marc H. Hedrick - Encinitas CA, US
Marc H. Hedrick - Encinitas CA, US
Assignee:
Cytori Therapeutics, Inc. - San Diego CA
International Classification:
C12N 5/00, A01N 63/00
US Classification:
424 937, 435366, 435325, 606 1, 606131, 604 19, 604 22
Abstract:
Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
Methods Of Using Regenerative Cells In The Treatment Of Musculoskeletal Disorders
US Patent:
2010030, Dec 2, 2010
Filed:
Aug 9, 2010
Appl. No.:
12/853110
Inventors:
Marc H. Hedrick - Encinitas CA, US
John K. Fraser - San Diego CA, US
Susan Lynn Riley - San Diego CA, US
Ronda Elizabeth Schreiber - Poway CA, US
John K. Fraser - San Diego CA, US
Susan Lynn Riley - San Diego CA, US
Ronda Elizabeth Schreiber - Poway CA, US
Assignee:
CYTORI THERAPEUTICS, INC. - San Diego CA
International Classification:
A61K 35/12, A61P 19/02, A61P 19/04, A61P 19/08
US Classification:
424 937
Abstract:
Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.
Systems And Methods For Separating And Concentrating Adipose Derived Stem Cells From Tissue
US Patent:
7514075, Apr 7, 2009
Filed:
Jun 25, 2004
Appl. No.:
10/877822
Inventors:
Marc H. Hedrick - Encinitas CA, US
John K. Fraser - San Diego CA, US
Michael J. Schulzki - Rancho Santa Fe CA, US
Bobby Byrnes - Carlsbad CA, US
Grace Carlson - San Francisco CA, US
Robert K. Shanahan - Carlsbad CA, US
John K. Fraser - San Diego CA, US
Michael J. Schulzki - Rancho Santa Fe CA, US
Bobby Byrnes - Carlsbad CA, US
Grace Carlson - San Francisco CA, US
Robert K. Shanahan - Carlsbad CA, US
Assignee:
Cytori Therapeutics, Inc. - San Diego CA
International Classification:
A01N 63/00
US Classification:
424 937, 435325, 435366, 606 1, 606131, 604 19, 604 22
Abstract:
Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e. g. , stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
Systems And Methods For Isolating And Using Clinically Safe Adipose Derived Regenerative Cells
US Patent:
2012026, Oct 18, 2012
Filed:
Apr 20, 2012
Appl. No.:
13/452349
Inventors:
Marc H. Hedrick - Encinitas CA, US
John K. Fraser - San Diego CA, US
Michael J. Schulzki - Rancho Santa Fe CA, US
Bobby Byrnes - Carlsbad CA, US
Grace Carlson - San Francisco CA, US
Rhonda Elizabeth Schreiber - Poway CA, US
Isabella Wulur - Rancho Cucamonga CA, US
John K. Fraser - San Diego CA, US
Michael J. Schulzki - Rancho Santa Fe CA, US
Bobby Byrnes - Carlsbad CA, US
Grace Carlson - San Francisco CA, US
Rhonda Elizabeth Schreiber - Poway CA, US
Isabella Wulur - Rancho Cucamonga CA, US
Assignee:
CYTORI THERAPEUTICS, INC. - SAN DIEGO CA
International Classification:
C12M 1/12
US Classification:
4352831
Abstract:
Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
Systems And Methods For Manipulation Of Regenerative Cells Separated And Concentrated From Adipose Tissue
US Patent:
2009030, Dec 10, 2009
Filed:
May 30, 2006
Appl. No.:
12/302787
Inventors:
Marc H. Hedrick - Encinitas CA, US
John K. Fraser - San Diego CA, US
John K. Fraser - San Diego CA, US
Assignee:
CYTORI THERAPEUTICS, INC. - San Diego CA
International Classification:
A61K 35/12, C12N 5/00, C12M 1/00, C12N 13/00, A61P 43/00
US Classification:
424 937, 435325, 4352831, 4351739
Abstract:
The invention provides methods for manipulating regenerative cells from adipose tissue. Specifically, it provides methods for enrichment of desired cells and enhancement of their therapeutic effects.
Methods Of Using Adipose Tissue-Derived Cells In Augmenting Autologous Fat Transfer
US Patent:
2012030, Dec 6, 2012
Filed:
Aug 17, 2012
Appl. No.:
13/588989
Inventors:
Marc H. Hedrick - Encinitias CA, US
John K. Fraser - San Diego CA, US
John K. Fraser - San Diego CA, US
Assignee:
CYTORI THERAPEUTICS, INC. - SAN DIEGO CA
International Classification:
A61K 35/12, A61P 3/06, A61P 17/00, A61P 9/00, A61P 1/00
US Classification:
424 937
Abstract:
Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.