Inventors:
John Burnett - Rochester MN, US
Horng Chen - Rochester MN, US
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
International Classification:
A61K 38/18, A61K 31/519
US Classification:
514012000, 514252160, 514262100
Abstract:
This document provides methods and materials related to PDE V inhibitors, natriuretic polypeptides, and combinations thereof. For example, compositions containing one or more PDE V inhibitors in combination with one or more natriuretic polypeptides are provided herein. In addition, methods for using PDE V inhibitors, natriuretic polypeptides, and combinations thereof to influence heart or renal activities within a mammal are provided herein.