Inventors:
Lisa Marie Miller - Rocky Point NY, US
Randy J. Smith - Wading River NY, US
John B. Warren - Port Jefferson NY, US
Donald Elliott - Hampton Bays NY, US
Assignee:
Brookhaven Science Associates, LLC - Upton NY
International Classification:
G01N 23/223, G01N 23/04
Abstract:
The invention relates to a fiducial marker having a marking grid that is used to correlate and view images produced by different imaging modalities or different imaging and viewing modalities. More specifically, the invention relates to the fiducial marking grid that has a grid pattern for producing either a viewing image and/or a first analytical image that can be overlaid with at least one other second analytical image in order to view a light path or to image different imaging modalities. Depending on the analysis, the grid pattern has a single layer of a certain thickness or at least two layers of certain thicknesses. In either case, the grid pattern is imageable by each imaging or viewing modality used in the analysis. Further, when viewing a light path, the light path of the analytical modality cannot be visualized by viewing modality (e. g. , a light microscope objective).