Inventors:
John W. Belmont - Houston TX, US
Frederick A. Fletcher - Ventura CA, US
Alice J. Chen - Houston TX, US
Roland Jurecic - Key Biscayne FL, US
Tse-Hua Tan - Houston TX, US
Guisheng Zhou - Houston TX, US
Assignee:
Amgen Inc. - Thousand Oaks CA
Baylor College of Medicine - Houston TX
International Classification:
A61K 31/7052, C07H 21/00, C12N 15/55, C12N 15/63, C12N 5/07, C12N 1/00, C12N 9/16, C07K 16/00, C12Q 1/42, G01N 33/53, A61P 9/10, A61P 13/12, A61P 1/16, A61P 11/00, A61P 19/02, A61P 29/00, A61P 37/06
US Classification:
514 44 R, 536 221, 536 232, 4353201, 435325, 435243, 435196, 5303879, 5303873, 435 21, 435 78
Abstract:
The present invention provides novel JNK activating phosphatase polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, antibodies and methods for producing JNK activating phosphatase polypeptides. Also provided for are methods for the diagnosis and treatment of diseases associated with JNK activating phosphatase polypeptides.