Inventors:
Michael Welsh - Riverside IA, US
John Wemmie - Iowa City IA, US
International Classification:
A61K038/00, A61K031/00, C12Q001/00, G01N033/53, G01N033/567
US Classification:
514/012000, 435/007200, 435/004000, 514/001000
Abstract:
Novel compositions for modulating acid-sensing ion channels (ASIC) function comprising ASIC, ASIC, and BNC1 and derivatives thereof; methods for modulating ASIC function and methods for treating cognitive disorders and for memory enhancement using the novel compositions of the invention; and a method for increasing synaptic plasticity are described.