JOHN A MACOVIAK
Medical Practice in La Jolla, CA

6585689, Jul 1, 2003

Sep 11, 2000

09/658741

John A. Macoviak - La Jolla CA
Wilfred J. Samson - Saratoga CA
Steve G. Baker - Sunnyvale CA
Karl Van Dyk - Freemont CA

Cardeon Corporation - Cupertino CA

A61M 500

60410307, 60410105

The present invention provides an aortic catheter having an upstream occlusion member positioned in the ascending aorta between the coronary arteries and the brachiocephalic artery and a downstream anchoring member positioned in the descending aorta, downstream of the aortic arch. The upstream occlusion member is in the form of a narrow, disk-shaped inflatable balloon. The downstream anchoring member may be a larger inflatable balloon or other anchoring structure that provides sufficient friction to prevent migration of the balloon catheter in the upstream or downstream direction. In addition, an arch perfusion lumen, a corporeal perfusion lumen and a cardioplegia lumen are provided for performing selective perfusion and cardioplegic arrest.

2006010, May 18, 2006

Oct 21, 2005

11/255529

Timothy Machold - Moss Beach CA, US
David Scott - Redwood City CA, US
David Rahdert - San Francisco CA, US
David Tholfsen - San Leandro CA, US
Robert Chang - Belmont CA, US
John Macoviak - La Jolla CA, US

A61B 17/12, A61F 2/24

600037000, 623002370, 606139000

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial adjustability and retrievability years after implant. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize an adjustable bridge stop to secure the implant, and the methods of implantation employ various tools.

6139517, Oct 31, 2000

Dec 14, 1998

9/212580

John A. Macoviak - La Jolla CA
Wilfred J. Samson - Saratoga CA
James J. Leary - Sunnyvale CA
Brady D. Esch - San Jose CA

Cardeon Corporation - Cupertino CA

A61M 500, A61M 2900

604 8

A perfusion shunt apparatus and methods are described for isolating and selectively perfusing a segment of a patient's cardiovascular system and for directing circulatory flow around the isolated segment. An aortic perfusion shunt apparatus is configured for deployment within a patient's aortic arch and methods are described for isolating the aortic arch vessels from the aortic lumen, for selectively perfusing the arch vessels with a fluid and for directing blood flow within the aortic lumen through a shunt past the isolated arch vessels. The perfusion shunt apparatus may be mounted on a catheter or cannula for percutaneous introduction or for direct insertion into a circulatory vessel, such as the aorta. The perfusion shunt apparatus has application for protecting a patient from embolic stroke or hypoperfusion during cardiopulmonary bypass or cardiac surgery and also for selectively perfusing the cerebrovascular circulation with oxygenated blood or with neuroprotective fluids in the presence of risk factors, such as head trauma or cardiac insufficiency. The perfusion shunt apparatus will also find application for selective perfusion of other organ systems within the body.

6893459, May 17, 2005

Sep 20, 2000

09/666617

John A. Macoviak - La Jolla CA, US

Ample Medical, Inc. - Foster City CA

A61F002/24

623 211, 623 238

A method of implanting a universal heart valve prosthetic anchor device for receipt of a mating occluder. The anchor device includes a pair of rings axially shiftable from a retracted to a deployed position. The anchor device further formed with a plurality of flexible retaining elements received within the anchor rings and which are capable of laterally downwardly outward movement upon deployment of the rings. The deployment tool includes an elongated tubular housing mounted at its distal end with radially outwardly diverging tines for reversible engagement with the anchoring rings. A wire is telescoped through the tines for actuation of the fork thereby causing deployment of the anchoring rings. Once placed at the desired location within the heart muscle, the deployment tool is actuated causing the anchor device to shift axially thereby causing the retainers to deploy outwardly and upwardly to secure the valve anchor in place at the heart valve annulus shelf.

2003023, Dec 25, 2003

Mar 18, 2003

10/391153

Wilfred Samson - Saratoga CA, US
John Macoviak - La Jolla CA, US

A61M031/00

604/103020

A method and device for perfusing an organ system is provided. The device may be further described as a catheter or cannula with an expandable flow control member positioned of the distal portion of the catheter shaft. The flow control member has a porous portion, and at least one impermeable portion, which prevent fluid from flowing out the ends of the flow control member. The flow control member is further characterized as having an interior chamber that is in fluid communication with a perfusion lumen that extends along the length of the catheter shaft and is in fluid communication with an external perfusion pump. The perfusion lumen is configured for providing flow to the interior of the flow control member, to create radial expansion thereof and to provide adequate flow to the arch vessels through said porous portion to sustain the metabolic demands of the brain.

2001002, Sep 6, 2001

Apr 3, 2001

09/825673

Brady Esch - San Jose CA, US
Janine Robinson - Half Moon Bay CA, US
John MacOviak - La Jolla CA, US
Wilfred Samson - Saratoga CA, US
Eric Olsen - Los Gatos CA, US

A61M031/00, A61M029/00

604/509000, 604/102020, 604/102030

The present invention includes an apparatus and methods for differentially perfusing a patient undergoing cardiopulmonary bypass. A cardiopulmonary bypass machine is configured to provide hypothermic oxygenated blood and normothermic oxygenated blood to an aortic balloon catheter. The catheter has arch perfusion ports and corporeal perfusion ports and is introduced into a patient's aorta and navigated transluminally until the occlusion balloon is located in the descending aorta. The occlusion balloon is inflated and hypothermic oxygenated blood is perfused to the arch vessels while normothermic oxygenated blood is perfused to the corporeal circulation. This procedure offers the benefit of cerebral protection from embolic events during cardiopulmonary bypass surgery.

2009032, Dec 31, 2009

Sep 2, 2009

12/584272

Timothy R. Machold - Moss Beach CA, US
David J. Scott - Redwood City CA, US
David A. Rahdert - San Francisco CA, US
David Rainone Tholfsen - San Leandro CA, US
Robert T. Chang - Belmont CA, US
John A. Macoviak - La Jolla CA, US

A61F 2/24

623 237

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial adjustability and retrievability years after implant. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize an adjustable bridge stop to secure the implant, and the methods of implantation employ various tools.

2010016, Jun 24, 2010

Feb 17, 2010

12/658909

Robert T. Chang - Belmont CA, US
John A. Macoviak - La Jolla CA, US
David A. Rahdert - San Francisco CA, US
Timothy R. Machold - Moss Beach CA, US

A61F 2/24

623 211, 623 236

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.

6224617, May 1, 2001

Dec 17, 1998

9/213740

Vahid Saadat - Redwood Shores CA
John A. Macoviak - La Jolla CA

Angiotrax, Inc. - Sunnyvale CA

A61B 1732

606170

Apparatus and methods for defibrillating a heart in fibrillation are provided using apparatus that forms a plurality of transmural channels in a wall of the heart. The apparatus includes a single-use handpiece having a mechanical cutting head and means for stabilizing the cutting head in contact with the tissue. The handpiece is coupled by a disposable cable to a controller that houses a vacuum pump and mechanisms for driving the cutting head. The cutting head is adapted to cooperate with the vacuum pump to evacuate tissue severed during the channel forming process.